The concept that ovulation occurs in response to the action of the pituitary gonadotropins is widely accepted (Everett, 1961). Follicle-stimulating hormone (FSH) is usually regarded as necessary for the relatively slow process of follicle growth and maturation, whereas luteinizing hormone (LH) is considered responsible for the induction of ovulation. In most mammals, LH release from the pituitary is a relatively sudden and brief event. In the rabbit it occurs within 1 h or less following mating, and lasts approximately 60 min (Fee and Parker, 1929). In some spontaneously ovulating species, such as the rat, it lasts only 30 min, and the period of the night during which ovulation may occur is less than 2 h (Everett et al., 1949). Although in these species, the interval between LH release or injection and the rupture of the ovarian follicle is usually several hours (Young, 1961), luteotropin-induced changes in ovarian blood flow and steroid secretion are detectable less than 1 h after the administration of the purified hormone.
KeywordsLuteinizing Hormone Menstrual Cycle Ovarian Follicle Primordial Germ Cell Krebs Solution
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- Coutinho, E. M., and Maia, H. S. (1971), The contractile response of the human uterus, fallopian tubes, and ovary to prostaglandins in vivo, Fertil Steril.22:539.Google Scholar
- Desclin, L. (1949), Action des estrogenes sur l’ovaire chez le rat normal et hypophysecto- misé, CR. Soc. Biol. Fil.143:1004.Google Scholar
- Everett, J. W. (1961), The mammalian female reproductive cycle and its controlling mechanisms, in: Sex and Internal Secretions, Vol. II, p. 497 (W. C. Young, ed.), Williams and Wilkins, Baltimore.Google Scholar
- Fee, A. R., and Parkes, A. S. (1929), Studies on ovulation. I. The relation of the anterior pituitary body to ovulation in the rabbit, J. Physiol.57:383.Google Scholar
- Maia, H., Jr., and Coutinho, E. M. (1973), Contractilidad del ovario de cobaya, Acta Physiol. Lat. Am.23:326.137Google Scholar
- Mintz, B. (1957), Embryological development of primordial germ cells in the mouse: Influence of a new mutation, w i , J. Embryol. Exp. Morphol. 5:396.Google Scholar
- Mintz, B. (1958), Irradiation of primordial germ cells in the mouse embryo, Anat. Rec.130:341.Google Scholar
- Nalbandov, A. V. (1961), Mechanisms controlling ovulation of avian and mammalian follicles, in: Control of Ovulation, p. 122 (C. A. Villee, ed.), Pergamon Press, London.Google Scholar
- Rocereto, T., Jacobwits, D., and Wallach, E. E. (1969), Observations of spontaneous contractions of the cat ovary in vitro, Endocrinology54:1136.Google Scholar
- Virutamasen, P., Wright, B. S., and Wallach, M. D. (1973), Monkey ovarian contractility-Its relationship to ovulation, Fertil. Steril.24:163.Google Scholar
- Witschi, E. (1948), Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds. Contrib. Embryol. Carnegie Inst. (Wash.) 32:61.Google Scholar
- Young, W. C. (1961), The mammalian ovary, in: Sex and Internal Secretions, Vol. I, p. 449 (W. C. Young, ed.), Williams and Wilkins; Baltimore.Google Scholar