Ovarian Contractility

  • E. M. Coutinho
  • H. Maia
  • H. MaiaJr.
Part of the Basic Life Sciences book series (BLSC, volume 4)


The concept that ovulation occurs in response to the action of the pituitary gonadotropins is widely accepted (Everett, 1961). Follicle-stimulating hormone (FSH) is usually regarded as necessary for the relatively slow process of follicle growth and maturation, whereas luteinizing hormone (LH) is considered respon­sible for the induction of ovulation. In most mammals, LH release from the pituitary is a relatively sudden and brief event. In the rabbit it occurs within 1 h or less following mating, and lasts approximately 60 min (Fee and Parker, 1929). In some spontaneously ovulating species, such as the rat, it lasts only 30 min, and the period of the night during which ovulation may occur is less than 2 h (Everett et al., 1949). Although in these species, the interval between LH release or injection and the rupture of the ovarian follicle is usually several hours (Young, 1961), luteotropin-induced changes in ovarian blood flow and steroid secretion are detectable less than 1 h after the administration of the purified hormone.


Luteinizing Hormone Menstrual Cycle Ovarian Follicle Primordial Germ Cell Krebs Solution 
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  1. Coutinho, E. M. (1974), Ovarian contractility and ovulation, Research in Reproduction, 6:3.PubMedGoogle Scholar
  2. Coutinho, E. M., and Maia, H. S. (1971), The contractile response of the human uterus, fallopian tubes, and ovary to prostaglandins in vivo, Fertil Steril.22:539.Google Scholar
  3. Coutinho, E. M., and Maia, H. S. (1972), Effects of gonadotropins on motility of human ovary, Nature New Biol. 235:94.PubMedCrossRefGoogle Scholar
  4. Desclin, L. (1949), Action des estrogenes sur l’ovaire chez le rat normal et hypophysecto- misé, CR. Soc. Biol. Fil.143:1004.Google Scholar
  5. Everett, J. W. (1961), The mammalian female reproductive cycle and its controlling mechanisms, in: Sex and Internal Secretions, Vol. II, p. 497 (W. C. Young, ed.), Williams and Wilkins, Baltimore.Google Scholar
  6. Everett, J. W., Sawyer, C. H., and Markee, J. E. (1949), A neurogenic timing factor in control of the ovulatory discharge of luteinizing hormone in the rat, Endocrinology44:234.PubMedCrossRefGoogle Scholar
  7. Fee, A. R., and Parkes, A. S. (1929), Studies on ovulation. I. The relation of the anterior pituitary body to ovulation in the rabbit, J. Physiol.57:383.Google Scholar
  8. Huxley, H. E. (1973), Muscular contraction and cell motility, Nature (Lond.)243:445.CrossRefGoogle Scholar
  9. Maia, H., Jr., and Coutinho, E. M. (1973), Contractilidad del ovario de cobaya, Acta Physiol. Lat. Am.23:326.137Google Scholar
  10. Mintz, B. (1957), Embryological development of primordial germ cells in the mouse: Influence of a new mutation, w i , J. Embryol. Exp. Morphol. 5:396.Google Scholar
  11. Mintz, B. (1958), Irradiation of primordial germ cells in the mouse embryo, Anat. Rec.130:341.Google Scholar
  12. Nalbandov, A. V. (1961), Mechanisms controlling ovulation of avian and mammalian follicles, in: Control of Ovulation, p. 122 (C. A. Villee, ed.), Pergamon Press, London.Google Scholar
  13. Osvaldo-Decima, L. (1970), Smooth muscle in the ovary of the rat and monkey, J. Ultrastruct Res. 29:218.CrossRefGoogle Scholar
  14. Palti, Z., and Freund, M. (1972), Spontaneous contractions of the human ovary in vitro, J. Reprod. Fertil.28 113.PubMedCrossRefGoogle Scholar
  15. Rocereto, T., Jacobwits, D., and Wallach, E. E. (1969), Observations of spontaneous contractions of the cat ovary in vitro, Endocrinology54:1136.Google Scholar
  16. Virutamasen, P., Wright, B. S., and Wallach, M. D. (1973), Monkey ovarian contractility-Its relationship to ovulation, Fertil. Steril.24:163.Google Scholar
  17. Williams, P. C. (1945), Studies of the biological action of serum gonadotropin. II. Ovarian response after hypophysectomy and estrogen treatment, J. Endocrinol.4:131.CrossRefGoogle Scholar
  18. Witschi, E. (1948), Migration of the germ cells of human embryos from the yolk sac to the primitive gonadal folds. Contrib. Embryol. Carnegie Inst. (Wash.) 32:61.Google Scholar
  19. Young, W. C. (1961), The mammalian ovary, in: Sex and Internal Secretions, Vol. I, p. 449 (W. C. Young, ed.), Williams and Wilkins; Baltimore.Google Scholar

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • E. M. Coutinho
    • 1
  • H. Maia
    • 1
  • H. MaiaJr.
    • 1
  1. 1.Federal University of BahiaSalvadorBrasil

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