Mechanisms Involved in Penetration of Spermatozoa Through the Vestments of the Mammalian Egg

  • J. M. Bedford
Part of the Basic Life Sciences book series (BLSC, volume 4)


In the past, the mammal has been something of a poor relation among the various metazoa used by students of fertilization. Failure to recognize the need for capacitation of spermatozoa and the complicating factors of the internal site of fertilization, the somewhat rigorous environmental requirement for consistent success in fertilization in vitro, and the very few eggs ovulated at one time have all been at least partly responsible for our relatively poor knowledge of the physiology of mammalian fertilization. The last aspect-egg numbers-still presents a problem for many who are interested in pursuing the biochemistry of egg activation and early development in mammals.


Granulosa Cell Follicular Fluid Zona Pellucida Cumulus Cell Acrosome Reaction 
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Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • J. M. Bedford
    • 1
  1. 1.Departments of Obstetrics and Gynecology and AnatomyCornell University Medical CollegeNew YorkUSA

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