Advertisement

The Function of the Corpus Luteum in Primates

  • Elof D. B. Johansson
  • William T. K. Bosu
Part of the Basic Life Sciences book series (BLSC, volume 4)

Abstract

The corpus luteum in nonpregnant primates secretes progesterone and estrogens for a limited period of 14 days. In many lower animals, the uterus determines the life span of the corpus luteum (Anderson et al., 1969). The corpus luteum in women and rhesus monkeys will function during its full life span even if the uterus is removed (Beling et al., 1970; Neill et al., 1969). In the primate, the implanted blastocyst rapidly produces chorion gonadotropins that stimulate the dying corpus luteum to continue to produce progesterone and estrogens until the placenta is capable of taking over the function.

Keywords

Luteinizing Hormone Menstrual Cycle Rhesus Monkey Luteal Phase Corpus Luteum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Anderson, L. L., Bland, K. P., and Melampy, R. M. (1969), Comparative aspects of uterine—luteal relationships, Rec. Progr. Hormone Res. 25:51.Google Scholar
  2. Auletta, F. J., Caldwell, B. V., van Wagenen, G., and Morris, J. M. (1972), Effects of postovulatory estrogen on progesterone and prostaglandins F levels in the monkey, Contraception 6:411.PubMedCrossRefGoogle Scholar
  3. Beling, C. G., Marcus, S. L., and Markham, S. M. (1970), Functional activity of the corpus luteum following hysterectomy, J. Clin. Endocrinol. 30:30.CrossRefGoogle Scholar
  4. Bosu, W. T. K. (1974), Plasma levels of estrogens and progestins during the menstrual cycle and pregnancy in the rhesus monkey (Macaca mulatta): With special reference to sites of production during pregnancy, Dissertation, Royal Swedish Veterinary College, Stockholm.Google Scholar
  5. Bosu, W. T. K., and Johansson, E. D. B. (1974a), Effects of postovulatory norethindrone and estrogens on the plasma levels of estrogen and progesterone in rhesus monkeys, Contraception 9:357.PubMedCrossRefGoogle Scholar
  6. Bosu, W. T. K., and Johansson, E. D. B. (1974b), Effect of HCG on plasma levels of estrogens and progesterone during the luteal phase of the menstrual cycle in rhesus monkeys (Macaca mulatta),Int. J. Fertil. 19:28.PubMedGoogle Scholar
  7. Bosu, W. T. K., Holmdahl, T. H., Johansson, E. D. B., and Gemzell, C. (1972), Peripheral plasma levels of oestrogens, progesterone and 17α-hydroxyprogesterone during the menstrual cycle of the rhesus monkey, Acta Endocrinol. (Kbh.) 72:755.Google Scholar
  8. Bosu, W. T. K., Johansson, E. D. B., and Gemzell, C. (1973a), Peripheral plasma levels of oestrogens, progesterone and 17α-hydroxyprogesterone during gestation in the rhesus monkey, Acta Endocrinol. (Kbh.) 74:348.Google Scholar
  9. Bosu, W. T. K., Johansson, E. D. B., and Gemzell, C. (1973b), Ovarian steroid patterns in peripheral plasma during the menstrual cycle in rhesus monkey, Folia Primatol 29:218.CrossRefGoogle Scholar
  10. Bosu, W. T. K., Johansson, E. D. B., and Gemzell, C. (1973c), Patterns of circulatory oestrone, oestradiol-17β and progesterone during pregnancy in the rhesus monkey, Acta Endocrinol. (Kbh.) 74:132.Google Scholar
  11. Christie, D. W., and Bell, E. T. (1971), Endocrinology of the oestrus cycle in the bitch, J. Small Anim. Pract. 12:383.PubMedCrossRefGoogle Scholar
  12. Edqvist, L.-E., and Johansson, E. D. B. (1972), Radioimmunoassay of oestrone and oestradiol in human and bovine peripheral plasma, Acta Endocrinol. (Kbh.) 71:716.Google Scholar
  13. Gore, B. Z., Caldwell, B. V., and Speroff, L. (1973), Estrogen-induced human luteolysis, J. Clin. Endocrinol 36:615.CrossRefGoogle Scholar
  14. Gustavii, B. (1973), Studies on the mode of action of intra-amniotically and extra- amniotically injected hypertonic saline in therapeutic abortion, Acta bstet. Gynecol. Scand. (suppl.) 25:1.Google Scholar
  15. Hoffman, F. (1960), Untersuchungen über die hormonale Beeinfluss- und der Lebensdauer des Corpus Luteum in Cyklus der Frau, Geburtsh. Frauenheilk. 20:1153.Google Scholar
  16. Johansson, E. D. B. (1969), Progesterone levels in peripheral plasma during the luteal phase of the normal menstrual cycle measured by a rapid competitive protein binding technique, Acta Endocrinol. (Kbh.) 61:592.Google Scholar
  17. Johansson, E. D. B. (1973), Inhibition of the corpus luteum function in women with large doses of diethylstilbestrol, Contraception 8:27.CrossRefGoogle Scholar
  18. Johansson, E. D. B., and Gemzell, C. (1971), Plasma levels of progesterone during the luteal phase in normal women treated with synthetic oestrogens (RS 2874, F 6103 and ethinyl oestradiol), Acta Endocrinol. (Kbh.) 68:551.Google Scholar
  19. Johansson, E. D. B., Wide, L., and Gemzell, C. (1971), Plasma levels of luteinizing hormone (LH), human chorionic gonadotrophin (HCG), progesterone (P) and estradiol-17β (E2) around implantation in women, Excerpta Med. 234a: 48.Google Scholar
  20. Karsch, F. J., Krey, L. C, Weick, R. F., Dierschke, D. J., and Knobil, E. (1973), Functional luteolysis in the rhesus monkey: The role of estrogen, Endocrinology 92:1148.PubMedCrossRefGoogle Scholar
  21. Knobil, E. (1973), On the regulation of the primate corpus luteum, Biol. Reprod. 8:246.Google Scholar
  22. Knobil, E., Neill, J. D., and Johansson, E. D. B. (1968), Influence of hypophysectomy, sham hypophysectomy and other surgical procedures on luteal function in the rhesus monkey, Endocrinology 52:410.CrossRefGoogle Scholar
  23. Koering, M. J. (1969), Cyclic changes in ovarian morphology during the menstrual cycle in Macaca mulatta, Am. J. Anat. 126:13.CrossRefGoogle Scholar
  24. Neill, J. D., Johansson, E. D. B., and Knobil, E. (1969), Failure of hysterectomy to influence the normal pattern of cyclic progesterone secretion in the rhesus monkey, Endocrinology 84:464.PubMedCrossRefGoogle Scholar
  25. Nillius, S. J., Gemzell, C, Johansson, E. D. B., and Wide, L. (1973), Monitoring treatment with human gonadotrophins or the synthetic decapeptide LH-releasing hormone, in: Gonadotrophins and Gonadal Steroids (Crosignani, P. G., ed.), Milan, in press.Google Scholar
  26. Thorneycroft, I. H., and Stone, S. C. (1972), Radioimmunoassay of serum progesterone in women receiving oral contraceptive steroids, Contraception 5:129.PubMedCrossRefGoogle Scholar
  27. Vande Wiele, R. L., Bogumil, J., Dyrenfurth, I., Ferin, M., Jewelewicz, R., Warren, M., Rizkallah, T., and Mikhail, G. (1970), Mechanisms regulating the menstrual cycle in women, Rec. Progr. Hormone Res. 26:63.Google Scholar

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • Elof D. B. Johansson
    • 1
  • William T. K. Bosu
    • 1
  1. 1.Primate Laboratory for Research in Reproduction, Department of Obstetrics and GynecologyUniversity HospitalUppsalaSweden

Personalised recommendations