Contractility of Myometrial Transplants

  • Gorm Wagner
Part of the Basic Life Sciences book series (BLSC, volume 4)


Long-term observation of activity of the myometrium during pregnancy, parturition, and Puerperium in the woman is for obvious reasons difficult to carry out. The individual factors that might influence the initiation of parturition are not possible to study in situ, as the tissue is continuously subject to changes of mechanical, hormonal, and nervous character. In vitro studies of isolated strips of myometrium have rendered information of great importance, but this technique gives only an impression of the immediate situation and never of the preceding or following states of the same tissue. Therefore, the ideal system would permit in vivo study of individual factors having myometrial influence. The technique of grafting seems to have been overlooked for its possibilities in the study of the physiology of the myometrium.


Spontaneous Activity Threshold Dose Single Spike Spike Potential Spontaneous Delivery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bouin, P., and Courrier, R. (1929), La greffe des cornes utérines chez le lapin: Leur réaction aux hormones genitales, Arch. Anat. Microsc. Morphol Exp.25:189–197.Google Scholar
  2. Clark, E. R., Kirby-Smith, H. T., Rex, R. O., and Williams, R. G. (1930), Recent modifications in the method of studying living cells and tissues in the transparent chambers inserted in the rabbit’s ear,Anat. Rec.47:187–211.CrossRefGoogle Scholar
  3. Qiff, W. J., Martin, J. D., and Michael, C. A. (1963), Use of ear chamber with uterine muscle transplants to differentiate myometrial and vascular activity, Nature (Lond.)199:399–400.CrossRefGoogle Scholar
  4. Djørup, A., Nielsen, J. F., and Wagner, G. (1970), Implantable FM-telemetry transmitter for long-term registration of biopotentials, Dan. Med. Bull.17:136–137.PubMedGoogle Scholar
  5. Kaiser, I. H. (1948), Effect of atropine and estrogens on intraocular uterine transplants in the rabbit, Bull. Johns Hopkins Hosp.82:429–445.PubMedGoogle Scholar
  6. Markee, J. E. (1932), An analysis of the rhythmic vascular changes in the uterus of the rabbit, Am. J. Physiol.100:274–378.Google Scholar
  7. Michael, C. A., and Cliff, W. J. (1964), Response of myometrial autografts in the rabbit ear chamber to oxytocin during pregnancy, Aust. N.Z. J. Obstet. Gynaecol.4:107–112.CrossRefGoogle Scholar
  8. Nielsen, J. F., and Wagner, G. (1972), Implantable FM-telemetry transmitters for registration of biopotentials, in: Biotelemetry,pp. 360–364 (H. P. Kimmich and J. A. Vos, eds.), Meander N. V., Leiden.Google Scholar
  9. Sandison, J. C. (1924), A new method for the microscopic study of living growing tissues by the introduction of a transparent chamber in the rabbit’s ear, Anat. Rec.28:281–287.CrossRefGoogle Scholar
  10. Wagner, G. (1969), Electrical and mechanical activity in myometrial grafts in the rabbit, Acta Physiol. Scand.76:lA–2A.Google Scholar
  11. Wagner, G. (1971), Induction of abortion in the rabbit by hydrocortison-acetate, Acta Endocrinol. (Kbh.) (suppl.)155:89.Google Scholar
  12. Wagner, G. (1974a), Autotransplantation of rabbit myometrium into ear-chamber and registration of its activity, Eur. J. Physiol, in press.Google Scholar
  13. Wagner, G. (1974b), Electrical activity of grafted myometrium and its recording by radiotelemetry in unrestrained rabbits, J. Physiol. (Lond.), in press.Google Scholar
  14. Wagner, G. (1975), Function of myometrial graft at time of parturition in the rabbit, Acta endocr., in manuscript.Google Scholar
  15. Williams, R. G. (1967), The transparent chamber method as applied to rabbit ears, in: In Vivo Techniques in Histology, pp. 113–136 (G. H. Bourne, ed.), Williams and Wilkins, Baltimore.Google Scholar

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • Gorm Wagner
    • 1
  1. 1.Institute of Medical Physiology BUniversity of CopenhagenCopenhagenDenmark

Personalised recommendations