Capacitation of Mammalian Spermatozoa

  • C. Barros
Part of the Basic Life Sciences book series (BLSC, volume 4)


The need for a physiological change in mammalian spermatozoa in the female genital tract as a prerequisite for fertilization was first recognized by Austin (1951) and Chang (1951) in the rabbit, and the change was termed “capacita­tion” (Austin, 1952). They found that if epididymal or ejaculated spermatozoa were introduced into the oviduct of the female rabbit before ovulation, eggs were fertilized. However, when the spermatozoa were introduced into the female after ovulation, few-if any-eggs were fertilized. In other words, the eggs lost the ability to be fertilized before the spermatozoa became capacitated.


Follicular Fluid Acrosome Reaction Golden Hamster Sperm Head Sperm Capacitation 
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Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • C. Barros
    • 1
  1. 1.Department of BiologyUniversity of HoustonHoustonUSA

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