Permeability Studies with Hemodialysis Membranes

  • Elias Klein
  • J. K. Smith
  • F. F. Holland
Part of the Polymer Science and Technology book series (PST, volume 6)


The clinical demonstration of hemodialysis as a treatment methodology (1,2) and the development of permanently implantable blood access cannulae (3) have evolved into a broadly based dialysis technology. In addition to the generally known use of hemodialysis in the amelioration of the effects of uremia, clinical dialysis has been used in the treatment of acute poisoning episodes, the reduction of serum barbiturate levels, and as a means of achieving rapid serum electrolyte balance (4).


Cellulose Acetate Void Volume Void Volume Fraction Residual Renal Function Permeability Study 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Kolff, W.J. and Berk, H.T.J., Acta Fed. Scand., 117, 121 (1944).Google Scholar
  2. 2.
    Kolff, W.J., Circulation, 15, 285 (1957).Google Scholar
  3. 3.
    Scribner, R.H., Quinton, W. and Dillard, D., Trans. Am. Soc. Art. Int. Organs, 6, 104 (1960).Google Scholar
  4. 4.
    Knepshield, J.H., Schreiner, G.E., Lowenthal, D.T. and Gelfand, M.C., Trans. Am. Soc. Art. Int. Organs, 19, 590 (1973).Google Scholar
  5. 5.
    Chemical Engineering Symposium Series, “The Artificial Kidney”, Am. Inst. Chem. Eng., 84, (1968).Google Scholar
  6. 6.
    Farrell, P.C. and Babb, A.L., J. Biomed. Mater. Res., 7, 275 (1973).CrossRefGoogle Scholar
  7. 7.
    Colton, D.K., Smith, K.A., Merrill, E.W. and Farrell, P.C., J. Biomed. Mater. Res., 5, 459 (1971).Google Scholar
  8. 8.
    Craig, L.C. and Koenigsberg, W.J., Phys. Chem., 65, 166 (1961).Google Scholar
  9. 9.
    Wendt, R.P., Toups, R.J., Smith, J.K., Leger, N. and Klein, E., I and EC Fundamentals, 10, 406 (1971).Google Scholar
  10. 10.
    Fisher, B.S., Higley, W.S., Cantor, P.A. and Stone, W., Trans. Am. Soc. Art. Int. Organs, 19, 429 (1973).Google Scholar
  11. 11.
    Wilke, C.R. and Chang, P., AIChEJ, 1, 264 (1965).Google Scholar
  12. 12.
    Babb, A.L., Popovich, R.P., Christopher, T.G., Scribner, B.H., The Genesis of the Square-Meter Hypothesis, Trans. Am. Soc. Art. Int. Organs, 17, 81 (1971).Google Scholar
  13. 13.
    Babb, A.L., Farrell, P.C., Uvelli, D.A., Scribner, B.H., Hemodialyzer Evaluation by Examination of Solute Molecular Spectra, Trans. Am. Soc. Art. Int. Organs, 18, 98 (1972).Google Scholar
  14. 14.
    Babb, A.L., Farrell, P.C., Strand, M.J., Uvelli, D.A., Milutinovic, J., Scribner, B.H., Residual Renal Function and Chronic Hemodialysis Therapy, Proc. of CD and T Forum, 11, 142 (1972).Google Scholar
  15. 15.
    Kjellstrand, C.M., Evans, R.L., Petersen, R.J., Rust, L.W., Shideman, J., Buselmeier, T.F. and Tozelle, L.T., Considerations of the Middle Molecule Hypothesis, Proc. of CD and T Forum, 11, 127 (1972).Google Scholar
  16. 16.
    Edson, H., Keen, M., and Gotch, F., Comparative Solute Transport and Therapeutic Effectiveness of Multiple Point Support and Standard Kiil Hemodialyzers, Trans. Am. Soc. Art. Int. Organs, 18, 113 (1972).Google Scholar
  17. 17.
    Sargent, J.A., Gotch, F.A., Caskey, T.L., Keen, M., Landau, J.I., Look, A.T., and Seid, M.A., Studies on the Molecular Etiology of Uremia using High Flux Cellulose Acetate Dialyzers, Third Annual Progress Report, Dow Chemical Co., submitted to Artificial Kidney Program, NIAMDD, 1973.Google Scholar
  18. 18.
    Gotch, F.A., Sargent, J.A., Keen, M.L., Seid, M. and Foster, R., Proc. CDT Forum, 1973 (in press).Google Scholar
  19. 19.
    Cavanaugh, K.L., “Physiological Transport Pa-ameters in the Patient-Artificial Kidney System” Thesis, U. of Texas, May, 1973.Google Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Elias Klein
    • 1
  • J. K. Smith
    • 1
  • F. F. Holland
    • 1
  1. 1.Gulf South Research InstituteNew OrleansUSA

Personalised recommendations