Hormonal Control of the Menstrual Cycle and Ovulation in the Rhesus Monkey

  • E. Knobil
Part of the ALZA Conference Series book series (ALZA, volume 2)


In primates, as in all other vertebrates, cyclic reproductive phenomena represent the outcome of complex, and still imperfectly understood, functional neuroendocrine interactions involving the ovarian hormones, the gonadotrophic hormones of the adenohypophysis and the hypophysiotrophic hormones of the hypothalamus. The following summary largely focuses on our own studies designed to describe the dynamics of the endocrine events throughout the menstrual cycle and to elucidate their control in the rhesus monkey (Macaca mulatta).


Luteinizing Hormone Menstrual Cycle Rhesus Monkey Corpus Luteum Luteinizing Hormone Level 
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  1. 1.
    Atkinson L.E., Bhattacharya A.N., Monroe S.E., Dierschke D.J. & Knobil E.: Endocrinology 87 (1970) 847.CrossRefGoogle Scholar
  2. 2.
    Atkinson L.E., Hotchkiss J., Fritz G.R., Surve A.H. & Knobil E.: Biol. Reprod. 5 (1971) 95.Google Scholar
  3. 3.
    Bhattacharya A.N., Dierschke D.J., Yamaji T. & Knobil E.: Endocrinology 90 (1972) 778.CrossRefGoogle Scholar
  4. 4.
    Dierschke D.J., Bhattacharya A.N., Atkinson L.E. & Knobil E.: Endocrinology 87 (1970) 850.CrossRefGoogle Scholar
  5. 5.
    Hopper B. & Tullner W.W.: Endocrinology 86 (1970) 1225.CrossRefGoogle Scholar
  6. 6.
    Hotchkiss J., Atkinson L.E. & Knobil E.: Endocrinology 89 (1971) 177.CrossRefGoogle Scholar
  7. 7.
    Johansson E.D.B., Neill J.D. & Knobil E.: Endocrinology 82 (1968) 143.CrossRefGoogle Scholar
  8. 8.
    Knobil E., Neill J.D. & Johansson E.D.B.: Endocrinology 82 (1968) 410.CrossRefGoogle Scholar
  9. 9.
    Knobil E., Dierschke D.J., Yamaji T., Karsch F J., Hotchkiss J. & Weick R.F. In: Saxena B.B., Ed. Gonadotrophins. John Wiley and Sons, Inc. (1972) in press.Google Scholar
  10. 10.
    Krey L.C., Yamaji T., Butler W.R. & Knobil E.: Fed. Proc. 31 (1972) 276.Google Scholar
  11. 11.
    Monroe S.E., Peckham W.D., Neill J.D. & Knobil E.: Endocrinology 86 (1970a) 1012.CrossRefGoogle Scholar
  12. 12.
    Monroe S.E., Atkinson L.E. & Knobil E.: Endocrinology 87 (1970b) 453.CrossRefGoogle Scholar
  13. 13.
    Neill J.D. & Knobil E.: Endocrinology 90 (1972) 34.CrossRefGoogle Scholar
  14. 14.
    Neill J.D., Johansson E.D.B. & Knobil E.: Endocrinology 81 (1967a) 1161.CrossRefGoogle Scholar
  15. 15.
    Neill J.D., Johansson E.D.B., Datta J.K. & Knobil E.: J. Clin. Endocr. & Metab. 27 (1967b) 1167.CrossRefGoogle Scholar
  16. 16.
    Neill J.D., Johansson E.D.B. & Knobil E.: Endocrinology 84 (1969a) 464.CrossRefGoogle Scholar
  17. 17.
    Neill J.D., Johansson E.D.B. & Knobil E.: Endocrinology 84 (1969b) 45.CrossRefGoogle Scholar
  18. 18.
    Schneider H.P.G. & McCann S.M. In: Bargman W. & Scherrer B., Eds. Aspects of Neuroendocrinology. Springer Verlag, Berlin (1970) p. 177.CrossRefGoogle Scholar
  19. 19.
    Vande Wiele R.L., Bogumil J., Dyrenfurth I., Ferin M., Jewelewicz R., Warren M., Rizkallah T. & Mikhail G.: Recent Progr. Hormone Res. 26 (1970) 63.Google Scholar
  20. 20.
    Yamaji T., Dierschke D.J., Hotchkiss J., Bhattacharya A.N., Surve A.H. & Knobil E.: Endocrinology 89 (1971) 1034.CrossRefGoogle Scholar
  21. 21.
    Yamaji T., Dierschke D.J., Bhattacharya A.N. & Knobil E.: Endocrinology 90 (1972) 771.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • E. Knobil
    • 1
  1. 1.Department of PhysiologyUniversity of Pittsburgh School of MedicinePittsburghUSA

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