Use of Prostaglandins in the Preparation of Blood Components

  • C. R. Valeri
  • C. G. Zaroulis
  • J. C. Rogers
  • R. I. Handin
  • L. D. Marchionni
Part of the Alza Conference Series book series (AEMB, volume 195B)


With recent increased understanding of the cellular physiology of red cells and platelets, and with development of large scale methods for plasma fractionation, the concept of component therapy in clinical medicine has evolved. This approach involves separation and individual storage of cellular and plasma components. In order to separate whole blood into its components shortly after collection centrifugation is necessary to prepare red cell concentrates, platelet concentrates, and platelet-poor plasma (PPP); separation can be achieved by either serial or continuous centrifugation (Graw et al, 1971; Jones, 1968; Tullis et al, 1967 and 1968).


Blood Component Platelet Concentrate Osmotic Fragility Platelet Recovery Autologous Platelet 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • C. R. Valeri
    • 1
  • C. G. Zaroulis
    • 1
  • J. C. Rogers
    • 1
  • R. I. Handin
    • 1
  • L. D. Marchionni
    • 1
  1. 1.Naval Blood Research LaboratoryChelseaUSA

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