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Structural Studies in Solution on the Combining Site of the Myeloma Protein MOPC 315

  • Raymond A. Dwek

Abstract

One of the great triumphs of structural immunologists is that many of the ideas of structure and function, now verified by X-ray studies, had been proposed on the basis of chemical data. These ideas included the basic two-chain immunoglobulin structure, the location of the antigen-binding site, and the concept of domain structure. These features are summarized in Fig. 1, for an IgG molecule.

Keywords

Nuclear Magnetic Resonance Electron Spin Resonance Electron Spin Resonance Spectrum Nuclear Magnetic Resonance Spectrum Difference Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Raymond A. Dwek
    • 1
  1. 1.Department of BiochemistryOxford UniversityOxfordEngland

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