Advertisement

Models for the Study of Tissue Deposition and Synthesis of Lipoproteins (Lecture III)

  • K. W. Walton
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 15)

Abstract

Efforts have been made, using a wide variety of animal species, to produce an acceptable animal model of human atherosclerosis. No single model is accepted universally as reproducing all aspects of the condition in humans (for review, see Ref.1) although primate models, and especially those involving the apes, such as the chimpanzees, probably approach this ideal most closely because both the lipid composition (2) and the immunological characteristics (3) of their lipoproteins are very similar to those of man.

Keywords

Arterial Wall Relative Permeability Intestinal Epithelial Cell Tissue Deposition Experimental Atherosclerosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Wissler, R.W. and Vesselinovitch, D. (1974) In Atherosclerosis III (eds. Schettler, G. and Weizel, A.) pp. 319–325, Springer Verlag, Berlin.Google Scholar
  2. 2.
    Blaton, V. and Peeters, H. (1976) Adv. Exper. Med. Biol., 67, 33.Google Scholar
  3. 3.
    Walton, K.W., Hitchens, J., Valente, A.J. and Blaton, V. (1977) Nature (Lond.) - in press.Google Scholar
  4. 4.
    Walton K.W., Thomas C. and Dunkerley, D.J. (1973) J. Pathol., 109, 271.PubMedCrossRefGoogle Scholar
  5. 5.
    Shore, B. and Shore V. (1960) J. Lipid Res., 1, 321.PubMedGoogle Scholar
  6. 6.
    Camejo, G., Bosch, V., Arreaza, C. and Mendez, H.C., (1973) J. Lipid Res., 14, 61.PubMedGoogle Scholar
  7. 7.
    Camejo, G., Bosch, V. and Lopez, A. (1974) Atherosclerosis, 19, 139.PubMedCrossRefGoogle Scholar
  8. 8.
    Walton, K.W., Dunkerley, D.J., Johnson, A.G., Khan, M.K., Morris, C.J. and Watts, R.B. (1976) Atherosclerosis, 23. 117.PubMedCrossRefGoogle Scholar
  9. 9.
    Walton, K.W. and Williamson, N. (1968) J. Atheroscler.Res. 8, 599.PubMedCrossRefGoogle Scholar
  10. 10.
    Walton, K.W. (1973) Nutr. Metab., 15, 37.PubMedCrossRefGoogle Scholar
  11. 1l.
    Walton, K.W. and Dunkerley, D.J. (1974) J. Pathol., 114, 217.PubMedCrossRefGoogle Scholar
  12. 12.
    Shore B. and Shore V. (1976) Adv. Exper.Med. Biol., 67, 123.Google Scholar
  13. 13.
    Keys, A. (1963) In Atherosclerosis and its Origin (Ed. Sandler, M. and Bourne, G.H.) pp. 263–299. Academic Press, New York.Google Scholar
  14. 14.
    Windmueller, H.A. and Spaeth, A.E. (1972) J. Lipid Res., 13, 92.PubMedGoogle Scholar
  15. 15.
    Walton, K.W., Morris, C.J., Bradby, G.V.H. and Pagnan, A. (1977) Nature (Lond) - in pressGoogle Scholar
  16. 16.
    Hamilton, R.H. (1972) Adv. Exper. Med. Biol., 26, 7.Google Scholar
  17. 17.
    Carlson, L.A. and Böttiger, L.E. (1972) Lancet, 1, 865PubMedCrossRefGoogle Scholar
  18. 18.
    Dawber, T.R., Kannel, W.B., Revotskie, N. and Kagan, A. (1962) Proc. R. Soc. Med., 55, 265.PubMedGoogle Scholar
  19. 19.
    Heptinstall, R.H., Barkley, H. and Porter, K.A. (1958) Angiology, 9, 84.PubMedCrossRefGoogle Scholar
  20. 20.
    Heath, D., Wood, E.H., Dushane, J.W. and Edwards, J.E. (1960) Lab. Invest., 9, 259.PubMedGoogle Scholar
  21. 21.
    Walton, K.W., Williamson, N. and Johnson, A.G. (1970) J. Pathol., 101, 205.PubMedCrossRefGoogle Scholar
  22. 22.
    Walton, K.W., Slaney, O.F. and Ashton, F. - in preparation.Google Scholar
  23. 23.
    Burch, G.E. and De Pasquale, N.P. (1964) Amer. J. Med., 37, 159.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • K. W. Walton
    • 1
  1. 1.Department of Experimental PathologyUniversity of BirminghamEngland

Personalised recommendations