Models for the Study of Tissue Deposition and Synthesis of Lipoproteins (Lecture III)
Efforts have been made, using a wide variety of animal species, to produce an acceptable animal model of human atherosclerosis. No single model is accepted universally as reproducing all aspects of the condition in humans (for review, see Ref.1) although primate models, and especially those involving the apes, such as the chimpanzees, probably approach this ideal most closely because both the lipid composition (2) and the immunological characteristics (3) of their lipoproteins are very similar to those of man.
KeywordsArterial Wall Relative Permeability Intestinal Epithelial Cell Tissue Deposition Experimental Atherosclerosis
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