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Assay of Lipoprotein Lipase in Postheparin Plasma after Suppression of the Hepatic Triglyceride Lipase with Sodium Dodecyl Sulfate

  • Marietta L. Baginsky
  • Flora Wu
  • W. Virgil Brown
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 15)

Abstract

Lipoprotein lipase (LPL), released by heparin into the circulating blood, is thought to originate from the capillary endothelium of a variety of tissues, including muscle and adipose tissue (1). Much evidence suggests that this enzyme is of primary importance in the degradation and removal of triglyceride from plasma chylomicrons and very low density lipoproteins (2–4). Assay of LPL in postheparin plasma has been complicated by the presence of a second triglyceride lipase which is of hepatic origin (5–7). The function of this hepatic triglyceride lipase (H-TGL) in triglyceride clearance has not been elucidated, though it is possible that it plays a role in the removal of partially degradated lipoproteins following LPL action.

Keywords

Sodium Dodecyl Sulfate Lipoprotein Lipase Protamine Sulfate Sodium Dodecyl Sulfate Solution Triglyceride Lipase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Marietta L. Baginsky
    • 1
  • Flora Wu
    • 1
  • W. Virgil Brown
    • 1
  1. 1.Department of Medicine, School of MedicineUniversity of CaliforniaLa JollaUSA

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