Physiological Roles of Prostaglandins in Reproduction

  • N. L. Poyser
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 13)


It is now over 40 years since prostaglandins were detected in secretions of human and sheep vesicular glands (von Euler, 1936). Bergström, Samuelsson and co-workers have since found seminal plasma to contain many different prostaglandins, with PGE1 and PGE2 being the most abundant in both human and sheep semen. The physiological significance of seminal prostaglandins in reproduction is still not clear. However, two reports have shown that seminal plasma from infertile men, for whom no obvious reason can be found for their infertility, contains significantly less PGE than normal (Bygdeman, Fredricsson, Svanborg and Samuelsson, 1970; Collier, Flower and Stanton, 1975). The picture has become more complicated recently by the findings that 19-OH PGE1 and 19-OH PGE2 are the major components of human semen, being present in larger quantities than PGEx and PGE2 (Taylor and Kelly, 1974; Jonsson, Middleditch and Desiderio, 1975).


Luteinizing Hormone Luteal Phase Seminal Plasma Luteinizing Hormone Level Human Endometrium 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • N. L. Poyser
    • 1
  1. 1.Department of PharmacologyUniversity of EdinburghEdinburghUK

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