Transcription of the Nuclear Genome of Acetabularia

  • Hans-Georg Schweiger
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 12)


As early as 50 years ago it was suggested that there are chemical transmitters between the genetic information of the cell nucleus and morphogenesis. Hämmerling was one of the very first who developed such a hypothesis and called these transmitters “ morphogenetische Substanzen” (Hämmerling, 1932). The existence of such “ morphogenetische Substanzen” was concluded from experiments which were performed on the unicellular and uninuclear green alga Acetabularia.The most important among these experiments lead to the observation that even in the absence of the nucleus, the green alga Acetabularia is still capable of performing morphogenesis. The morphogenetic agent was localized within the cytoplasm and was shown to exhibit a pronounced polarity with a high activity being found in the apical part and a low activity in the basal part of the cell. Since Hämmerling’s early experiments, a number of investigations yielded indirect evidence that “morphogenetische Substanzen” are identical with mRNA; however, final proof for this hypothesis is still lacking.


Nuclear Genome Amplification Site Pulse Experiment Transcription Product Elsevier Scientific Publishing Company 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Hans-Georg Schweiger
    • 1
  1. 1.Max-Planck-Institut für ZellbiologieWilhelmshavenGermany

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