The Synthesis of Chloroplast Proteins

  • R. John Ellis
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 12)


It is a fundamental feature of the organisation of eukaryotic cells that they contain organelles possessing genetic systems additional to the one located in the nucleus. In the case of chloroplasts, the fact that these organelles contain both DNA and ribosomes was demonstrated first in 1962. It soon became apparent that both these components are present in significant quantities. Thus the chloroplast genome has the potential capacity for encoding about 125 proteins, each of molecular weight 50 000, whilst chloroplast ribosomes can represent up to 50% of the total ribosomal complement of leaves [1,2]. The existence of such quantities of chloroplast DNA and ribosomes prompts the question as to their roles in the formation of chloroplasts. Which genes are encoded in chloroplast DNA? Which proteins are synthesised by chloroplast ribosomes? I believe it is necessary to answer such simple direct questions before it is possible to tackle meaningfully the more interesting but far more complex question as to the molecular basis of chloroplast development.


Large Subunit Chloroplast Genome Chloroplast Protein Label Amino Acid Chloroplast Envelope 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ellis, R.J. and Hartley, M.R. (1974) Nucleic Acids (K. Burton, ed.), MTP International Review of Science Series in Biochemistry, vol. 6, 323 — Medical and Technical Publishing Co., Lancaster, and Butterworth, London.Google Scholar
  2. 2.
    Boulter, D., Ellis, R.J. and Yarwood, A. (1972) Biol. Rev. 47, 113–175.CrossRefGoogle Scholar
  3. 3.
    Bottomley, W., Spencer, D. and Whitfeld P.R. (1974) Arch. Bio-chem. Biophys. 164, 106–117.CrossRefGoogle Scholar
  4. 4.
    Morgenthaler, J.J. and Mendiola-Morgenthaler, L. (1976) Arch. Biochem. Biophys. 172, 51–58.PubMedCrossRefGoogle Scholar
  5. 5.
    Blair, G.E. and Ellis, R.J. (1973) Biochim. Biophys. Acta 319, 223–234.PubMedGoogle Scholar
  6. 6.
    Eaglesham, A.R.J, and Ellis, R.J. (1974) Biochim. Biophys. Acta 335, 396–407.Google Scholar
  7. 7.
    Joy, K.W. and Ellis, R.J. (1975) Biochim. Biophys. Acta 378, 143–151.PubMedGoogle Scholar
  8. 8.
    Ellis, R.J. (1975) Membrane Biogenesis 8, 247–278 (Tzagoloff, A., ed). Plenum Publishing Co., New York.CrossRefGoogle Scholar
  9. 9.
    Hartley, M.R., Wheeler, A. and Ellis, R.J. (1975) J. Mol. Biol. 91, 67–77.PubMedCrossRefGoogle Scholar
  10. 10.
    Wheeler, A.M. and Hartley, M.R. (1975) Nature 257, 66–67.PubMedCrossRefGoogle Scholar
  11. 11.
    Siddell, S.G. and Ellis, R.J. (1975) Biochem. J. 146, 675–685.PubMedGoogle Scholar
  12. 12.
    Ellis, A.J., Blair, G.E. and Hartley, M.R. (1973) Biochem. Soc. Symp. 38, 137–162.Google Scholar
  13. 13.
    Parenti, F. and Margulies, M.M. (1967) Plant physiol. 42, 1179–1168.PubMedCrossRefGoogle Scholar
  14. 14.
    Ellis, R.J. (1973) Comment. Plant Sci. 4, 29–38.Google Scholar
  15. 15.
    Gray, J.C. and Kekwick, R.G.D. (1974) Eur. J. Biochem. 44, 491–500.PubMedCrossRefGoogle Scholar
  16. 16.
    Mendiola-Morgenthaler, L.R., Morgenthaler, J.J. and Price, C.A. (1976) FEBS Letts. 62, 96–100.CrossRefGoogle Scholar
  17. 17.
    Ellis, R.J. (1973) Trans. Biochem. Soc. 1, 13–16.Google Scholar
  18. 18.
    Kung, S. (1976) Science 191, 429–434.PubMedCrossRefGoogle Scholar
  19. 19.
    Mackender, R.O. and Leech, R.M. (1970) Nature 228, 1347–1348.PubMedCrossRefGoogle Scholar
  20. 20.
    Highfield, P.E. and Ellis, R.J. (1976) Biochim. Biophys. Acta. (in press).Google Scholar
  21. 21.
    Ellis, R.J. (1975) Phytochem. 14, 89–93.CrossRefGoogle Scholar
  22. 22.
    Ellis, R.J. (1976) Perspectives in Experimental Biology Vol. 2, 283–298 (N. Sunderland, ed.) Pergamon Press, Oxford and New York.Google Scholar
  23. 23.
    Ellis, R.J. and MacDonald, I.R. (1970) Plant Physiol. 46, 227–232.PubMedCrossRefGoogle Scholar
  24. 24.
    Ellis, R.J. (1969) Science 163, 477–478.PubMedCrossRefGoogle Scholar
  25. 25.
    Blobel, G. and Dobberstein, B. (1975) J. Cell Biol. 67, 835–851.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • R. John Ellis
    • 1
  1. 1.Department of Biological SciencesUniversity of WarwickCoventryUK

Personalised recommendations