Endothelial Proliferation Factor

  • B. Haber
  • R. L. Suddith
  • H. T. Hutchison
  • P. J. Kelly
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 11)


The viability of the brain is predicated upon its blood supply. Nowhere is the process of vascularization of the brain more dramatically visualized than in the expansion of the capillary bed within and around tumors of the CNS (6). Recent evidence suggests that this endothelial proliferation (or neovascularization as it is often called) is mediated by a soluble factor (12) released by the growing tumor cells as proposed earlier by Algire (1). The new vessels are recruited by the tumor from the already existent host vasculature in the region of the tumor (1, 26).


Nerve Growth Factor Conditioned Medium Endothelial Proliferation Half Maximal Response Thymidine Label Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • B. Haber
    • 1
    • 2
    • 3
  • R. L. Suddith
    • 1
    • 2
    • 3
  • H. T. Hutchison
    • 1
    • 2
    • 3
  • P. J. Kelly
    • 1
    • 2
    • 3
  1. 1.Division of NeurobiologyThe Marine Biomedical InstituteUSA
  2. 2.Department of NeurologyUniversity of Texas Medical BranchGalvestonUSA
  3. 3.Department of Human Biological Chemistry and GeneticsUniversity of Texas Medical BranchGalvestonUSA

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