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α-Melanotropin Receptors: Non-Identical Hormonal Message Sequences (Active Sites) Triggering Receptors in Melanocytes, Adipoctytes and CNS Cells

  • Alex Eberle
  • Robert Schwyzer
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 11)

Abstract

α-Melanotropin (α-melanocyte-stimulating hormone, α-MSH), a pituitary tridecapeptide, exhibits strong effects on a variety of tissues. The best known is certainly the dramatic impact on the color change of cold-blooded vertebrates where α-MSH causes darkening of the skin by dispersion of the melanophore pigment granules. a-MSH seems also to control—at least partially—the pigmentation of mammals and men (35). Only a small number of extrapigmentary effects of α-melanotropin will be mentioned here as e.g. the lipolytic activity in rabbit adipose tissue (7, 45), the effects on learning and the central nervous system (11, 13, 46, 47, 58), and the activity on sebum secretion in the rat (49, 60).

Keywords

Lipolytic Response Sebum Secretion Squalus Acanthias Tetrapeptide Sequence National Biomedical Research Foundation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Alex Eberle
    • 1
  • Robert Schwyzer
    • 1
  1. 1.Institute of Molecular Biology and BiophysicsSwiss Federal Institute of Technology (ETH)ZürichSwitzerland

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