Structure and Function of Membranes and the Role of the Plasma Membrane in Metabolic Regulations

  • Efraim Racker
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 11)


Membranes are essential for life as we know it. It is very likely that the origin of life is associated with the formation of vesicular membranes. It is difficult to imagine that the most improbable of events, the creation of life, could have taken place without such a device of organization and concentration. Membranes are structures that envelop cells and intracellular organelles, thereby creating compartments. It was not Caesar, but a membrane who first said: divide and conquer. By protecting the delicate components of living protoplasm against a hostile environment, membranes have made the survival of a genetic apparatus possible and have made life liveable.


ATPase Activity Sarcoplasmic Reticulum Aerobic Glycolysis Ehrlich Ascites Tumor Cell Mitochondrial ATPase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    ALBERS, R. W., KOVAL, G. J. and SIEGEL, G. J. , Mol. Pharmacol. 4 (1968) 324.PubMedGoogle Scholar
  2. 2.
    BURK, D., WOODS, M. and HUNTER, J. , J. Natl. Cancer Inst. 38 (1967) 839.PubMedGoogle Scholar
  3. 3.
    GOLDIN, S. M. and TONG, S. W., J. Biol. Chem. 249 (1974) 5907.PubMedGoogle Scholar
  4. 4.
    HILDEN, S., RHEE, H. M. and HOKIN, L. E. , J. Biol. Chem, 249.(1974) 7432,PubMedGoogle Scholar
  5. 5.
    KAGAWA, Y. and RACKER, E. , J. Biol. Chem. 246 (1971) 5477.Google Scholar
  6. 6.
    LANG, E. R. and RACKER, E., Biochim. Biophys. Acta 333 (1974) 180.PubMedCrossRefGoogle Scholar
  7. 7.
    LINDENMAYER, G. E., LAUGHTER, A. H. and SCHWARTZ, A., Arch. Biochem. Biophys. 127 (1968) 187.PubMedCrossRefGoogle Scholar
  8. 8.
    MAC LENNAN, D. H., J. Biol. Chem. 245 (1970) 4508.Google Scholar
  9. 9.
    MAC LENNAN, D. H., YIP, C. C., ILES, G. H. and SEAMAN, P., Cold Spring Harbor Symp., Quant. Biol. 37 (1972) 469.CrossRefGoogle Scholar
  10. 10.
    MUELLER, P. , Energy Transducing Mechanisms (E. Racker, ed.) (1975) in press.Google Scholar
  11. 11.
    OESTERHELT, D. and STOECKENIUS, W. , Proc. Nat. Acad. Sci. USA 70 (1973) 2853.PubMedCrossRefGoogle Scholar
  12. 12.
    POST, R. L., KUME. S. and ROGERS, F. N. , Mechanisms in Bioener-getics (G. F. Azzone et al. eds) Academic Press (1973) 203.Google Scholar
  13. 13.
    PULLMAN, M. E. and MONROY, G. C. , J. Biol. Chem. 238 (1963) 3762.PubMedGoogle Scholar
  14. 14.
    RACKER, E. , J. Biol. Chem. 247 (1972) 8198.PubMedGoogle Scholar
  15. 15.
    RACKER, E., Dynamics of Energy-transducing Membranes (Ernster, Estabrook and Slater, eds.) Elsevier Scientific Publishing Co., Amsterdam, The Netherlands (1974) 269.Google Scholar
  16. 16.
    RACKER, E. , Biochemical Society Transactions (1975) in press.Google Scholar
  17. 17.
    RACKER, E. , Proceedings of 10th FEBS Symp., Paris. (1975) .Google Scholar
  18. 18.
    RACKER, E. and EYTAN, E. , J. Biol. Chem. (1975) in press.Google Scholar
  19. 19.
    SCHOLNICK, P., LANG, D. and RACKER, E. , J. Biol. Chem. 248 (1973) 5175.PubMedGoogle Scholar
  20. 20.
    SUOLINNA, E-M., LANG, D. R. and RACKER, E. , J. Natl. Cancer Inst. 53 (1974) 1515.PubMedGoogle Scholar
  21. 21.
    SWEENEY, M. J. , ASHMORE, J., MORRIS, H. P. and WEBER, G., Cancer Research 23 (1963) 995.PubMedGoogle Scholar
  22. 22.
    WARBURG, O., Uber den Stoffwechsel der Tumoren, Springer Verlag, Berlin (1926).Google Scholar
  23. 23.
    WHITTAM, R. and AGER, M. E., Biochem. J. 97 (1965) 214.PubMedGoogle Scholar
  24. 24.
    WU, R. and RACKER, E., J. Biol. Chem. 234 (1959) 1036.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Efraim Racker
    • 1
  1. 1.Section of Biochemistry, Molecular & Cell BiologyCornell UniversityIthacaUSA

Personalised recommendations