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Specific Binding and Ability of Vasoactive Intestinal Octacosa-Peptide (VIP) to Activate Adenylate Cyclase in Isolated Pancreatic Acinar Cells from the Guinea Pig

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Surface Membrane Receptors

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 11))

Abstract

This is probably the first instance in which the specific binding of a gastrointestinal hormone to a digestive cell other than the hepatocyte has been studied. The vasoactive intestinal octacosa-peptide (VIP) was recently isolated from porcine upper small intestine (19) and its amino acid sequence has been determined (4, 12).

Recipients of a scientific mission award from the Fonds National de la Recherche Scientifique of Belgium

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References

  1. AMSTERDAM, A. and JAMIESON, J. D., J. Cell Biol. 63 (1974) 1037, 1057.

    Article  PubMed  CAS  Google Scholar 

  2. BATAILLE, D., FREYCHET, P. and ROSSELIN, G., Endocrinology 95 (1974) 713.

    Article  PubMed  CAS  Google Scholar 

  3. BIRNBAUMER, L. and POHL, S. L., J. Biol. Chem. 248 (1973) 2056.

    PubMed  CAS  Google Scholar 

  4. BODANSZKY, M., KLAUSNER, Y. S. and SAID, S. I., Proc. Nat. Acad. Sci. USA 70 (1973) 382.

    Article  PubMed  CAS  Google Scholar 

  5. DE MEYTS, P., ROTH, J., NEVILLE, D. M., GAVIN, J. R. and LESNIAK, M. A., Biochem. Biophys. Res. Commun. 55 (1973) 154.

    Article  PubMed  Google Scholar 

  6. DESBUQUOIS, B., LAUDAT, M. H. and LAUDAT, P., Biochem. Biophys. Res. Commun. 53 (1973) 1187.

    Article  Google Scholar 

  7. DESBUQUOIS, B., Eur. J. Biochem, 46 (1974) 439.

    Article  PubMed  CAS  Google Scholar 

  8. DESCHODT-LANCKMAN, M., ROBBERECHT, P., DE NEEF, P., LABRIE, F. and CHRISTOPHE, J., Gastroenterology 68 (1975) 318.

    PubMed  CAS  Google Scholar 

  9. FRANDSEN, E. K. and MOODY, A. J., Horm. Metab. Res. 5 (1973) 196.

    Article  Google Scholar 

  10. HUNTER, W. M., and GREENWOOD, F. C, Nature 194 (1972) 495.

    Article  Google Scholar 

  11. MAROIS, C., NORISSET, J. and DUNNIGAN, J. , Rev. Can. Biol. 31 (1972) 253.

    PubMed  CAS  Google Scholar 

  12. MUTT, V. and SAID, S. I., Eur. J. Biochem. 42 (1974) 581.

    Article  PubMed  CAS  Google Scholar 

  13. ROBBERECHT, P., DESCHODT-LANCKMAN, M., DE NEEF, P., BORGEAT, P. and CHRISTOPHE, J., FEBS Letters 43 (1974) 139.

    Article  PubMed  CAS  Google Scholar 

  14. RODBELL, M., BIRNBAUMER, L. and POHL, S. L., J. Biol. Chem. 245 (1970) 718.

    PubMed  CAS  Google Scholar 

  15. RODBELL, M., KRANS, H. M. J., POHL, S. L. and BIRNBAUMER, L., J. Biol. Chem. 246 (1971) 1861.

    PubMed  CAS  Google Scholar 

  16. RODBELL, M., LIN, M. C. and SALOMON, Y., J. Biol. Chem. 249 (1974) 59.

    PubMed  CAS  Google Scholar 

  17. ROTH, J., Metabolism 22 (1973) 1059.

    Article  PubMed  CAS  Google Scholar 

  18. RUTTEN, W. J., DE PONT, J. J. H. H. M. and BONTING, S. L., Biochim. Biophys. Acta 274 (1972) 201.

    Article  PubMed  CAS  Google Scholar 

  19. SAID, S. I, and MUTT, V., Eur. J. Biochem. 28 (1972) 199.

    Article  PubMed  CAS  Google Scholar 

  20. SALOMON, Y., LONDOS, C. and RODBELL, M., Anal. Biochem. 58 (1974) 541.

    Article  PubMed  CAS  Google Scholar 

  21. SCHWARTZ, C. J., KIMBERG, D. V., SHEERIN, H. E., FIELD, M. and SAID, S. I. (1975) in press.

    Google Scholar 

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Author information

Author notes

  1. Jean Christophe & Patrick Robberecht

    Present address: Department of Biochemistry and Nutrition, University of Brussels Medical School, 1000, Brussels, Belgium

Authors and Affiliations

  1. Section on Gastroenterology, Digestive Diseases Branch, National Institute of Arthritis, Metabolism, and Digestive Diseases, Bethesda, Md., 20014, USA

    Jean Christophe, Patrick Robberecht, Thomas P. Conlon & Jerry D. Gardner

Authors
  1. Jean Christophe
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  2. Patrick Robberecht
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  3. Thomas P. Conlon
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  4. Jerry D. Gardner
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Editor information

Editors and Affiliations

  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Ralph A. Bradshaw , William A. Frazier , Ronald C. Merrell  & David I. Gottlieb , ,  & 

  2. University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA

    Ruth A. Hogue-Angeletti

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© 1976 Plenum Press, New York

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Christophe, J., Robberecht, P., Conlon, T.P., Gardner, J.D. (1976). Specific Binding and Ability of Vasoactive Intestinal Octacosa-Peptide (VIP) to Activate Adenylate Cyclase in Isolated Pancreatic Acinar Cells from the Guinea Pig. In: Bradshaw, R.A., Frazier, W.A., Merrell, R.C., Gottlieb, D.I., Hogue-Angeletti, R.A. (eds) Surface Membrane Receptors. NATO Advanced Study Institutes Series, vol 11. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2772-1_19

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  • DOI: https://doi.org/10.1007/978-1-4684-2772-1_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2774-5

  • Online ISBN: 978-1-4684-2772-1

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