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Specific Binding and Ability of Vasoactive Intestinal Octacosa-Peptide (VIP) to Activate Adenylate Cyclase in Isolated Pancreatic Acinar Cells from the Guinea Pig

  • Jean Christophe
  • Patrick Robberecht
  • Thomas P. Conlon
  • Jerry D. Gardner
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 11)

Abstract

This is probably the first instance in which the specific binding of a gastrointestinal hormone to a digestive cell other than the hepatocyte has been studied. The vasoactive intestinal octacosa-peptide (VIP) was recently isolated from porcine upper small intestine (19) and its amino acid sequence has been determined (4, 12).

Keywords

Specific Binding Adenylate Cyclase Acinar Cell Adenylate Cyclase Activity Pancreatic Acinar Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Jean Christophe
    • 1
  • Patrick Robberecht
    • 1
  • Thomas P. Conlon
    • 1
  • Jerry D. Gardner
    • 1
  1. 1.Section on Gastroenterology, Digestive Diseases BranchNational Institute of Arthritis, Metabolism, and Digestive DiseasesBethesdaUSA

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