Specific Binding and Ability of Vasoactive Intestinal Octacosa-Peptide (VIP) to Activate Adenylate Cyclase in Isolated Pancreatic Acinar Cells from the Guinea Pig
This is probably the first instance in which the specific binding of a gastrointestinal hormone to a digestive cell other than the hepatocyte has been studied. The vasoactive intestinal octacosa-peptide (VIP) was recently isolated from porcine upper small intestine (19) and its amino acid sequence has been determined (4, 12).
KeywordsSpecific Binding Adenylate Cyclase Acinar Cell Adenylate Cyclase Activity Pancreatic Acinar Cell
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- 21.SCHWARTZ, C. J., KIMBERG, D. V., SHEERIN, H. E., FIELD, M. and SAID, S. I. (1975) in press.Google Scholar