Comparative Studies on the Molecular Basis for a Viral Involvement in Murine and Human Mammary Adenocarcinoma

  • R. Michalides
  • S. Feldman
  • S. Spiegelman
  • J. Schlom
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 5)


The etiologic role of RNA tumor viruses in a variety of cancers in animals is well established. In many instances proof of causation has been achieved by the inoculation of purified cell-free virus preparations in experiments that satisfy Koch’s postulates. Indirect evidence has been accumulating during the last decade that RNA tumor viruses similar to the mouse mammary tumor virus (MMTV) may be involved in the etiology of human breast cancer.


Mammary Tumor Human Milk Mouse Mammary Tumor Virus Nucleic Acid Sequence Glycerol Gradient 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • R. Michalides
    • 1
  • S. Feldman
    • 2
  • S. Spiegelman
    • 2
  • J. Schlom
    • 3
  1. 1.Meloy Laboratories, Inc.SpringfieldUSA
  2. 2.Columbia UniversityNew YorkUSA
  3. 3.National Institutes of Health-National Cancer InstituteBethesdaUSA

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