Smooth Muscle pp 141-162 | Cite as

Isolation and Identification of Smooth Muscle Contractile Proteins

  • Y. Nonomura
  • S. Ebashi


Twenty-five years have passed since the pioneering work of Csapó (1948, 1949) in extracting a protein resembling skeletal muscle actomyosin from uterine smooth muscle. It is rather surprising that during these years only a small number of papers have been published dealing with the biochemical aspects of smooth muscle, as compared with the large number on skeletal muscle. It is difficult to describe a routine method for the isolation and identification of smooth muscle contractile proteins since preparative methods reported to date have scarcely been confirmed by other investigators and almost all methods therefore remain unestablished.


Thin Filament Contractile Protein Thick Filament Smooth Muscle Myosin Myosin Molecule 
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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Y. Nonomura
    • 1
  • S. Ebashi
    • 1
  1. 1.Department of Pharmacology, Faculty of MedicineUniversity of TokyoHongo, TokyoJapan

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