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Smooth Muscle pp 419-438 | Cite as

Nerve—Muscle Preparations of Genito-Urinary Muscle (Other Than Vas Deferens)

  • Jean M. Marshall

Abstract

Nerve—muscle preparations of other smooth muscles in the genito-urinary tract have been studied less extensively than those of the vas deferens. One reason is that, unlike the vas deferens, these other muscles usually show considerable spontaneous, myogenic activity. It is assumed that neural influences modulate rather than initiate this activity so that the effects of nerve stimulation are more subtle and therefore more difficult to analyze than in the vas deferens. Another reason is that the innervation density, determined histochemically and biochemically (Labay et al., 1970; Marshall, 1970), is considerably less in genito-urinary muscles other than the vas deferens. Thus the electrophysiological investigations of neuroeff’ector transmission at the cellular level are often more ambiguous and less predictable in the former muscles. Nevertheless, studies on nerve-muscle preparations from a variety of smooth muscles are of importance not only from a comparative pharmacological viewpoint, but also as a contribution to a better understanding of the role of the nervous system in the control and regulation of smooth muscle in general.

Keywords

Nerve Stimulation Intraluminal Pressure Uterine Horn Adrenergic Nerve Hypogastric Nerve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bass, P. and Callantine, M. R. 1964. Simultaneous recording of electrical and mechanical activity of the uterus in the unanaesthetized animal. Nature, 203:1367–1368.PubMedCrossRefGoogle Scholar
  2. Bohr, D. F. 1964. Electrolytes and smooth muscle contraction. Pharmacol. Rev., 16:85–113.PubMedGoogle Scholar
  3. Bower, E. A. 1966. The characteristics of spontaneous and evoked action potentials recorded from the rabbit’s uterine nerves. J. Physiol., 183:730–747.PubMedGoogle Scholar
  4. Brundin, J. 1965. Distribution and function of adrenergic nerves in the rabbit fallopian tube. Acta. Physiol.Scand., 66(Suppl. 259): 5–57.Google Scholar
  5. Burn, J. H. and Rand, M. J. 1960. The relation of circulating noradrenaline to the effect of sympathetic stimulation. J. Physiol., 150:295–305.PubMedGoogle Scholar
  6. Burnstock, G. and Campbell, G. 1963. Comparative physiology of the vertebrate autonomic nervous system. II. Innervation of the urinary bladder of the ringtail possum (pseudocheirus peregrinus). J. Exp. Biol., 40:421–436.PubMedGoogle Scholar
  7. Carpenter, F. G. 1963. Excitation of rat urinary bladder by coaxial electrodes and by chemical agents. Am. J. Physiol., 204:727–731.PubMedGoogle Scholar
  8. Coutinho, E. M., Hugo, M., and Filho, J. A. 1970. Response of the human fallopian tube to adrenergic stimulation. Fertility and Sterility, 21:590–594.PubMedGoogle Scholar
  9. Csapo, Á. 1969. The luteo-placental shift, the guardian of pre-natal life. Postgrad. Med. J., 45:57–64.PubMedCrossRefGoogle Scholar
  10. Csapo, Á.. 1970. The diagnostic significance of the intrauterine pressure. Obstet. Gynecol. Survey 25:403-435.Google Scholar
  11. Csapo, Á. and Takeda, H. 1963. Electrical activity of the paturient human uterus. Nature, 200:680–682.PubMedCrossRefGoogle Scholar
  12. Daniel, E. E. 1960. Effect of the placenta on the electrical activity of the cat uterus in vivo and in vitro.Am. J. Obstet. Gynec., 80:229–244.PubMedGoogle Scholar
  13. Dominic, J. A. and Reinke, D. A. 1968. Extraluminal force transducer for in-vivo measurement of rabbit uterine contractile activity. Fertility and Sterility, 19:645–953.Google Scholar
  14. Edge, N. D. 1955. A contribution to the innervation of the urinary bladder of the cat. J. Physiol., 127:54–68.PubMedGoogle Scholar
  15. Huković, S., Rand, M. S., and Vanov, S. 1965. Observations on an isolated innervated preparation of rat urinary bladder. Br. J. Pharmacol., 24:178–188.Google Scholar
  16. Labay, P., Boyarsky, S., Duarte-Escalante, O., and Grimes, J. H. 1970. The scientific concept of ureteral innervation: will it become aurologic concept? J. Urology, 103:37–40.Google Scholar
  17. Luduena, F. P. and Grigas, E. O. 1966. Pharmacological study of autonomic innervation of dog retractor penis. Am. J. Physiol., 210:435–444.PubMedGoogle Scholar
  18. Marshall, J. M. 1969. The effects of ovarian hormones on the uterine response to adrenergic nerve stimula¬tion and to adrenergic amines. In: Progesterone: Its Regulatory Effect on the Myometrium, pp. 89–105. Ed. by Wolstenholme, G. E. W. and Knight, J. Ciba Foundation Study Group 34. J. and A. Churchill, London.Google Scholar
  19. Marshall, J. M. 1970. Adrenergic innervation of the female reproductive tract: Anatomy, physiology and pharmacology. Rev. Physiol., 62:7–67.Google Scholar
  20. Miller, M. D. and Marshall, J. M. 1965. Uterine response to nerve stimulation: relation to hormonal status and catecholamines. Am. J. Physiol., 209:859–865.PubMedGoogle Scholar
  21. Nakanishi, H., Wansbrough, H., and Wood, C. 1967. Postganglionic sympathetic nerve innervating human fallopian tube. Am. J. Physiol., 213:613–619.PubMedGoogle Scholar
  22. Orlov, R. S. 1968. Nervous activation of smooth muscle cells of intact animals. Proc. Int. Union. Physiol. Sci., 6:146–147.Google Scholar
  23. Pennefather, J.N. and Isaac, P. F. 1967. The response of the isolated uterus of the guinea-pig to stimulation of the ovarian nerves during the oestrous cycle. Aust. J. Exp. Biol. Med. Sci., 45:229–244.CrossRefGoogle Scholar
  24. Porter, D. G. 1971. Quantitative changes in myometrial activity in the guinea-pig during pregnancy. J. Reprod. Fert., 27:219–226.CrossRefGoogle Scholar
  25. Rüsse, M. W. and Marshall, J. M. 1970. Uterine response to adrenergic nerve stimulation in the guinea pig. Biol. Reprod, 3: 13–22.Google Scholar
  26. Setekleiv, J. 1964. Uterine motility of the estrogenized rabbit. III. Response to hypogastric and splanchnic nerve stimulation. Acta Physiol. Scand., 62:137–149.Google Scholar
  27. Sullivan, S. F. and Marshall, J. M. 1970. Quantitative evaluation of effects of exogenous amines on contractility of human myometrium in vitro. Am. J. Obstet. Gynecol., 107:139–149.PubMedGoogle Scholar
  28. Ursillo, R. C. 1961. Electrical activity of the isolated nerve-urinary bladder strip preparation of the rabbit. Am. J. Physiol, 201:408–412.PubMedGoogle Scholar
  29. Ursillo, R. C. and Clark, B. B. 1956. The action of atropine on the urinary bladder of the dog and on the isolated nerve-bladder strip preparation of the rabbit. J. Pharmacol. Exp. Ther., 118:338–347.PubMedGoogle Scholar
  30. Vanov, S. 1965. Responses of the rat urinary bladder in situ to drugs and to nerve stimulation. Br. J. Pharmacol, 24:591–600.Google Scholar
  31. Varagić, V. 1956. An isolated rabbit hypogastric-nerve-uterus preparation, with observations on the hypogastric transmitter. J. Physiol., 132:92–99.PubMedGoogle Scholar
  32. Vogt, M. 1965. Transmitter released in the cat uterus by stimulation of the hypogastric nerves. J. Physiol, 179:163–171.PubMedGoogle Scholar
  33. Woodbury, J. W. and Brady, A. J. 1956. Intracellular recording from moving tissues with a flexibly mounted ultramicroelectrode. Science, 123:100–101.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Jean M. Marshall
    • 1
  1. 1.Division of Biological and Medical SciencesBrown UniversityProvidenceUSA

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