The two major objectives of the function of the human sweat glands are:
  1. 1.

    To assist in the maintenance of body temperature through the evaporation of the sweat on the surface of the skin.

  2. 2.

    To aid in the maintenance of water, electrolyte, and nitrogen balance by excretion of excess water, electrolytes, and nitrogenous compounds.



Cystic Fibrosis Sweat Gland Eccrine Sweat Gland Excretory Duct Sweat Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Selected Reading—Human Sweat

  1. Rothman, S., Physiology and Biochemistry of the Skin, Univ. of Chicago Press, Chicago, Illinois (1954).Google Scholar
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  1. 1.
    Perry, T. L., Hansen, S., Diamond, S., Bullis, B., Mok, C., and Melancon, S. B., Volatile fatty acids in normal human physiological fluids, Clin. Chim. Acta 29: 369–374 (1970).CrossRefGoogle Scholar
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    Cage, G. W. and Dobson, R. L., Sodium secretion and reabsorption in the human eccrine sweat gland, J. Clin. Invest. 44: 1270–1276 (1965).CrossRefGoogle Scholar
  3. 3.
    Sato, K., Dobson, R. L., and Mali, J. W. H., Enzymatic basis for the active transport of sodium in the eccrine and sweat gland. Localization and characterization of Na K adenosine triphosphatase, J. Invest. Derm. 57: 10–16 (1971).CrossRefGoogle Scholar
  4. 4.
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    Komives, G. K., Robinson, S., and Roberts, J. T., Urea transfer across the sweat glands, J. Appl. Physiol. 21: 1681–1684 (1966).Google Scholar
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    Collins, K. J., The action of exogenous aldosterone on the secretion and composition of drug-induced sweat, Clin. Sci. 30: 207–221 (1966).Google Scholar
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  26. 26.
    Emrich, H. M., Stoll, E., Friolet, B., Colombo, J. P., Richterich, R., and Rossi, E., Sweat composition in relation to rate of sweating in patients with cystic fibrosis of the pancreas, Pediat. Res. b: 464–478 (1968).Google Scholar
  27. 27.
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  30. 30.
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  31. 31.
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  32. 32.
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  34. 34.
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  35. 35.
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  37. 37.
    Hager, Malecka, B. and Szezepanski, Z., Detection of mucoviscidosis hetero-zygotes by the bromide sweat test, Pol. Tyg. Lek. 24: 792–794 (1969).Google Scholar
  38. 38.
    Szczepanski, Z. and Hager-Maleckal, B., Determination of bromide in the sweat after oral administration of bromide preparations, Pol. Med. J. 6: 1507–1511 (1967).Google Scholar
  39. 39.
    Wilson, G. B., John, T. L., and Fonseca, J. R., Demonstration of serum protein differences in cystic fibrosis by isoelectric focusing in thin layer polyacrylamide gels, Clin. Chim. Acta 49: 79–91 (1973).CrossRefGoogle Scholar
  40. 40.
    Lewis, J. M., Bodansky, O., Birmingham, J., and Cohlan, S. Q., Comparative absorption, excretion and storage of oily and aqueous preparations of Vitamin A, J. Pediat. 31: 496–508 (1947).CrossRefGoogle Scholar
  41. 41.
    Andersen, D. H. and Early, M. V., Method of assaying trypsin suitable for routine use in diagnosis of congenital pancreatic deficiency, Am. J. Dis. Child. 63: 891 (1942).Google Scholar
  42. 42.
    Elam, J. F. and Palmer, R. E., An automated procedure for the determination of sweat electrolytes, Am. J. Clin. Pathol. 46: 65–68 (1966).Google Scholar
  43. 43.
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  44. 44.
    Szabo, L., Kenny, M. A., and Less, W., Direct measurement of chloride in sweat with an ion selective electrode, Clin. Chem. 19: 727–730 (1973).Google Scholar
  45. 45.
    Coltman, C. A., Jr., Rowe, N. J., and Atwell, R. J., The amino acid content of sweat in normal adults, Am. J. Clin. Nutr. 18: 373–378 (1966).Google Scholar
  46. 46.
    Hungerland, H. and Liappis, N., Study of the free amino acids in human exocrine sweat, Klin. Wschr. 50: 973–976 (1972).CrossRefGoogle Scholar
  47. 47.
    Miklaszewska, M., Comparative studies of free amino acids eccrine in sweat and plasma, Pol. Med. J. 7: 1313–1318 (1968).Google Scholar
  48. 48.
    Prasad, A. S., Schulert, A. R., Sandstead, H. H., Miale, A., Jr., and Farid, Z., Zinc, iron, and nitrogen content of sweat in normal and deficient subjects, J. Lab. Clin. Med. 62: 84–89 (1963).Google Scholar
  49. 49.
    Calloway, D. H., Odell, A. C. F., and Margen, S., Sweat and miscellaneous nitrogen losses in human balance studies, J. Nutr. 101: 775–786 (1971).Google Scholar
  50. 50.
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  51. 51.
    Fraki, J. E., Jansen, C. T., and Hopsu Havu, V. K., Human sweat kallikrein. Biochemical demonstration and chromatographic separation from several other esteropeptidases in the sweat, Acta Dermatol. Venereol. 50: 321–326 (1970).Google Scholar
  52. 52.
    Page, C. O., Jr. and Remington, J. S., Immunologic studies in normal human sweat, J. Lab. Clin. Med. 69: 634–650 (1967).Google Scholar
  53. 53.
    Jirka, M. and Masopust, J., Immunochemical behavior of proteins in human sweat, Biochem. Biophys. Acta 71: 217–218 (1963).Google Scholar
  54. 54.
    Astrand, I., Lactate content in sweat, Acta Physiol. Scand. 58: 359–367 (1963).CrossRefGoogle Scholar
  55. 55.
    Brown, G. and Dobson, R. L., Sweat sodium excretion in normal women, J. Appl. Physiol. 23: 97–99 (1967).Google Scholar
  56. 56.
    Consolazio, C. F., Matoush, L. O., Nelson, R. A., Isaac, G. J., and Canham, J. E., Comparisons of nitrogen, calcium and iodine excretion in arm and total body sweat, Am. J. Clin. Nutr. 18: 443–448 (1966).Google Scholar
  57. 57.
    Ahlmann, K. L., Eränkö, O., Karvonen, M. J., and Leppänen, V., Mineral composition of thermal sweat in healthy persons, J. Clin. Endocrinol. 13: 773–782 (1953).CrossRefGoogle Scholar
  58. 58.
    Levin, S., Shapira, E., Garin, T., Seligson, S., and Strassberg, D., Effect of age, ethnic background and disease on sweat chlorides, Israel J. Med. Sci. 2: 333–337 (1966).Google Scholar
  59. 59.
    Danton, R. A. and Nyhan, W. L., Concentrations of uric acid in the sweat of control and mongoloid children, Proc. Soc. Exp. Biol. Med. 121: 270–271 (1966).Google Scholar
  60. 60.
    Coltman, C. A., Jr. and Rowe, N. J., The iron content of sweat in normal adults, Am. J. Clin. Nutr. 18: 270–274 (1966).Google Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Samuel Natelson
    • 1
  • Ethan A. Natelson
    • 2
  1. 1.Department of BiochemistryMichael Reese Hospital and Medical CenterChicagoUSA
  2. 2.Baylor College of Medicine Methodist HospitalHoustonUSA

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