Fluid and Electrolyte Applications

  • Samuel Natelson
  • Ethan A. Natelson


The ultimate objective in studying fluid and electrolyte balance in the human is to place treatment in the diseased state on a rational basis. The many variables and areas of uncertainty make any method of calculation necessarily a rough estimate. However, if major deficits are corrected, normal function may be restored, in which case the homeostatic mechanisms of the body can take over and complete the adjustment. For example, at a pH of 7.1, in the adult, cell metabolism is severely impaired, and the central nervous system ceases to perform its normal function. Restoration to a pH of 7.4 and correction of other major deficits will often restore this function and reestablish a drive toward normal metabolism. The primary objective of fluid therapy is to restore the normal function of the homeostatic mechanisms.


Breast Milk Protein Hydrolysate Sodium Lactate Extracellular Fluid Volume Calcium Gluconate 
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Selected Reading—Fluid and Electrolyte Applications

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Samuel Natelson
    • 1
  • Ethan A. Natelson
    • 2
  1. 1.Department of BiochemistryMichael Reese Hospital and Medical CenterChicagoUSA
  2. 2.Baylor College of Medicine Methodist HospitalHoustonUSA

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