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Thermostating Capillary Cells for a Laser-Raman Spectrophotometer

  • G. J. ThomasJr.
  • J. R. Barylski

Abstract

An important application of laser-Raman spectroscopy is for the study of structures and interactions of biological macromolecules in aqueous solution.1 A number of nucleic acids, proteins, and related model compounds have recently been studied using this method.2–6 In such investigations, control of thesample temperature is critical because biopolymers generally undergo changes in conformation with temperature. Thermal control at the sample may also be required in other Raman applications.7

Keywords

Raman Spectrum Thermal Control Capillary Cell Centrifugal Distortion Brass Block 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. 1.
    G. J. Thomas, Jr. in Physical Techniques in Biological Research: Optical Techniques,G. Oster, Ed. (Academic, New York, 1970), 2nd ed., Vol. 1.Google Scholar
  2. 2.
    R. C. Lord and G. J. Thomas, Jr., Spectrochim. Acta 23A, 2551 (1967); Biochim. Biophys. Acta 142, 1 (1967); Dey. Appl. Spectrosc. 6, 179 (1968).CrossRefGoogle Scholar
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    B. Fanconi, B. Tomlinson, L. A. Nafie, W. Small, and W. L. Peticolas, J. Chem. Phys. 51, 3993 (1969).CrossRefGoogle Scholar
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    M. Smith, A. G. Walton, and J. L. Koenig, Biopolymers 8, 29, 173 (1969).Google Scholar
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    R. C. Lord and N. T. Wu, J. Mol. Biol. 50, (1970) (to be published).Google Scholar
  6. 6.
    G. J. Thomas, Jr., (unpublished).Google Scholar
  7. 7.
    J. B. Bates and W. A. Smith, Appl. Spectrosc. 23, 622 (1969).CrossRefGoogle Scholar
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    S. K. Freeman and D. O. Landon, Anal. Chem. 41, 398 (1969).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • G. J. ThomasJr.
    • 1
  • J. R. Barylski
    • 2
  1. 1.Department of ChemistrySoutheastern Massachusetts UniversityNorth DartmouthUSA
  2. 2.Department of Mechanical EngineeringSoutheastern Massachusetts UniversityNorth DartmouthUSA

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