Abstract
When consideration is given to recent advances and progress made in the treatment of cancer, little attention is directed toward those changes taking place that are probably as profound and as far reaching in consequence as are any in our time. To many—particularly those in other disciplines—the surgical approach to cancer is deemed anachronistic in concept. While categorically such may be true, the leading edge of that specialty is attempting to redefine the basis for cancer surgery so that it is in keeping with present understanding of tumor biology.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alexander, P., 1972, Tumor immunology in perspective, in: Frontiers of Radiation Therapy and Oncology (J. M. Vaeth, ed.), pp. 213–222, Karger, New York.
Alexander, P., and Hall, J. G., 1970, The role of immunoblasts in host resistance and immunotherapy of primary sarcomata, Adv. Cancer Res. 13:1.
Ashworth, R. T., 1869, A case of cancer in which cells similar to those in the tumours were seen in the blood after death, Aust. Med. J. 14:146.
Barski, G., and Youn, J. K., 1969, Evolution of cell-mediated immunity in mice bearing an antigenic tumor: Influence of tumor growth and surgical removal, J. Natl. Cancer Inst. 43:111.
Bartels, F., 1909, Das Lymphgefässystem, Gustav Fischer, Jena.
Bosner, G. M., 1945, Microscopical study of evolution of mouse mammary cancer—Effect of milk factor and comparison with human disease, J. Pathol. Bacteriol. 57:413.
Burnet, F. M., 1967, Immunological aspects of malignant disease, Lancet 1:1171.
Cheatle, G. L., and Cutler, M., 1931, Tumours of the Breast—Their Pathology, Symptoms and Diagnosis and Treatment, Lippincott, Philadelphia.
Currie, G. A., and Basham, C., 1972, Serum mediated inhibition of the immunological reactions of the patient to his own tumour: A possible role for circulating antigen, Br. J. Cancer 26:427.
Delarue, N. C., 1960, The free cancer cell, Can. Med. Assoc. J. 82:1175.
Dewys, W. D., 1972, Studies correlating the growth rate of a tumor and its metastases and providing evidence for tumor related systemic growth retarding factors, Cancer Res. 32:374.
Donovan, A. J., 1967, The effect of surgery on reticuloendothelial function, Arch. Surg. (Chicago) 94:247.
Everson, T. C., and Cole, W. H., 1966, Spontaneous Regression of Cancer, Saunders, Philadelphia.
Fisher, B., and Fisher, E. R., 1965, The biology of metastasis, in: Current Concepts in Surgery (J. H. Davis, ed.), pp. 321–351, McGraw-Hill, New York.
Fisher, B., and Fisher, E. R., 1966a, Transmigration of lymph nodes by tumor cells, Science 152:1397.
Fisher, B., and Fisher, E. R., 1966b, Interrelationship of hematogenous and lymphatic tumor cell dissemination, Surg. Gynecol. Obstet. 122:791.
Fisher, B., and Fisher, E. R., 1967a, The barrier function of the lymph node to tumor cells and erythrocytes. I. Normal nodes, Cancer 20:1907.
Fisher, B., and Fisher, E. R., 1967b, The barrier function of the lymph node to tumor cells and erythrocytes. II. Effect of X-ray, inflammation, sensitization and tumor growth, Cancer 20:1914.
Fisher, B., and Fisher, E. R., 1968, Role of the lymphatic system in dissemination of tumor, in: Lymph and the Lymphatic System, pp. 324–347, Charles C Thomas, Springfield, Ill.
Fisher, B., Saffer, E. A., and Fisher, E. R., 1972, Studies concerning the regional lymph node in cancer. III. Response of regional lymph node cells from breast and colon cancer patients to PHA stimulation, Cancer 30:1202.
Fisher, B., Saffer, E. A., and Fisher, E. R., 1974a, Studies concerning the regional lymph node in cancer. IV. Tumor inhibition by regional lymph node cells, Cancer 33:631.
Fisher, B., Wolmark, N., and Coyle, J., 1974b, Effect of Corynebacterium parvum on cytotoxicity of regional and non-regional lymph node cells from animal with tumors present and removed, J. Natl. Cancer Inst 53:1793.
Fisher, B., Saffer, E., and Fisher, E. R., 1974c, Studies concerning the regional lymph node in cancer. VII. Thymidine uptake by cells from nodes of breast cancer patients relative to axillary location and histopathologic discriminants, Cancer Res. 34:1668.
Fisher, B., Slack, N., Katrych, D. L., and Wolmark, N., 1975a, Ten year follow-up of breast cancer patients in a cooperative clinical trial evaluating surgical adjuvant chemotherapy, Surg. Gynecol. Obstet. 140:528.
Fisher, B., Carbone, P., Economou, S. G., Frelick, R., Glass, A., Lerner, H., Redmond, C., Zelen, M., Katrych, D. L., Wolmark, N., Band, P., Fisher, E. R., and other cooperating investigators, 1975b, 1-Phenylalanine mustard (l-PAM) in the management of primary breast cancer: A report of early findings, N. Engl. J. Med., 292:117.
Fisher, B., Wolmark, N., Coyle, J., and Saffer, E. A., 1976, Effect of a growing tumor and its removal on the cytotoxicity of macrophages from cultured bone marrow cells, Cancer Res. 36:2302.
Fisher, E. R., and Fisher, B., 1974, Some theoretical and practical considerations of metastases, Contemp. Surg. 4:85.
Fisher, E. R., and Turnbull, R. B., Jr., 1955, Cytologic demonstration and significance of tumor cells in the mesenteric venous blood in patients with colorectal carcinoma, Surg. Gynecol. Obstet. 100:102.
Fisher, E. R., Saffer, E. A., and Fisher, B., 1973, Studies concerning the regional lymph node in cancer. VI. Correlation of lymphocyte transformation of regional node cells and some histopathologic discriminants, Cancer 32:104.
Foote, F. W., and Stewart, F. W., 1945, Comparative studies of cancerous versus noncancerous breasts, Ann. Surg. 121:5.
Frindel, E., Malaise, E. P., Alpen, E., and Tubiana, M., 1967, Kinetics of Cell. proliferation of an experimental tumor, Cancer Res. 27:1122.
Gallager, H. S., and Martin, J. E., 1969, The study of mammary carcinoma by mammography and whole organ sectioning, Cancer 23:855.
Gershon, R. D., and Carter, R. L., 1969, Factors controlling concomitant immunity in tumor bearing hamsters: Effect of prior splenectomy and tumor removal, J. Natl. Cancer Inst. 43:533.
Graham, J. B., and Graham, R. M., 1955, Antibodies elicited by cancer in patients, Cancer 8:409.
Gray, H. J., 1939, Relation of the lymphatic vessels to the spread of cancer, Br. J. Surg. 26:462.
Haagensen, C. D., 1933, An exhibit of important books, papers, and memorabilia illustrating the evolution of the knowledge of cancer, Am. J. Cancer 18:42.
Halsted, W. S., 1890/1891, The treatment of wounds with especial reference to the value of the blood clot in the management of dead spaces, Johns Hopkins Hosp. Rep. 2:255.
Halsted, W. S., 1907, The results of radical operations for the cure of carcinoma of breast, Ann. Surg. 46:1.
Handley, W. S., 1922, Cancer of the Breast and Its Operative Treatment, A. Murray, London.
Hayward, O. S., 1965a, The history of oncology. I. Early oncology and the literature of discovery, Surgery 58:460.
Hayward, O. S., 1965b, The history of oncology. II. The society for investigating cancer, London, Surgery 58:586.
Hayward, O. S., 1965c, The history of oncology. III. America and the cancer lectures of Nathan Smith, Surgery 58:745.
Hellström, I., Hellström, K. E., and Sjögren, H. O., 1970, Serum mediated inhibition of cellular immunity to methylcholanthrene-induced murine sarcomas, Cell. Immunol. 1:18.
Heppner, G. H., 1972, In vitro studies on cell-mediated immunity following surgery in mice sensitized to syngeneic mammary tumors, Int. J. Cancer 9:119.
Hughes, L. E., and McKay, W. D., 1965, Suppression of the tubercular response in malignant disease, Br. Med. J. 2:1346.
Humphrey, L. J., Wingard, D. W., and Lang, R., 1969, The effect of surgery and anesthesia on the immunologic responsiveness of the rat, Surgery 65:946.
Humphrey, L. J., Frederickson, E. L., and Amerson, J. R., 1970, Effect of anesthesia and amputation on tumor and general immunity of the mouse, J. Surg. Res. 10:265.
Israel, L., Mugica, J., and Chahinian, P., 1973, Prognosis of early bronchogenic carcinoma: Survival curves of 451 patients after resection of lung cancer in relation to the results of the preoperative tuberculin skin test, Biomedicine 19:68.
Kramer, W. M., and Rush, B. F., 1973, Mammary duct proliferation in the elderly—A histopathologic study, Cancer 31:130.
Laird, A. K., 1964, Dynamics of tumor growth, Br. J. Cancer 18:490.
LeDran, H. F., 1757, Mémoires avec un précis de plusieurs observations sur le cancer, Mem. Acad. R. Chic. 3:1.
Long, L., Jonasson, O., Roberts, S., McGrath, R., McGrew, E., and Cole, W. H., 1960, Cancer cells in the blood; results of simplified isolation technique, AMA Arch. Surg. 80:910.
McCredie, J. A., Inch, W. R., Kruuv, J., and Watson, T. A., 1965, The rate of tumor growth in animals, Growth 29:331.
Mikulska, A. B., Smith, C., and Alexander, P., 1966, Evidence for an immunological reaction of the host directed against its own actively growing primary tumor, J. Natl. Cancer Inst. 36:29.
Morgagni, G. G., 1769, The Seats and Causes of Diseases Investigated by Anatomy, Miller and Cadell, London (translated by B. Alexander, reprinted by Hafner, 1960, for New York Academy of Medicine).
Nicholson, G. W., 1921, Carcinoma of breast, Br. J. Surg. 8:527.
Odili, J. L., and Taylor, G., 1971, Transience of immune responses to tumour antigens in man, Br. Med. J. 4:584.
Park, S. K., Brody, J. I., Wallace, H. A., and Blakemore, W. S., 1971, Immunosuppressive effect of surgery, Lancet 1:53.
Patey, D. H., 1967, A review of 146 cases of carcinoma of the breast operated on between 1930 and 1943, Br. J. Cancer 21:260.
Pilch, Y. H., and Riggins, R. S., 1966, Antibodies to spontaneous and MC-induced tumors in inbred mice, Cancer Res. 26:871.
Pool, E. H., and Dunlop, R. R., 1934, Cancer cells in bloodstream, Am. J. Cancer 21:99.
Riddle, P. R., 1967, Distributed immune reactions following surgery, Br. J. Surg. 54:882.
Ritchie, A. C., and Webster, D. R., 1961, Tumor cells in the blood, in: Proceedings of the Fourth Canadian Cancer Conference, Academic Press, New York.
Roberts, S., Jonasson, O., Long, L., McGrew, E. A., McGrath, R., and Cole, W. H., 1962, Relationship of cancer cells in the circulating blood to operation, Cancer 15:232.
Saba, T. M., 1970, Mechanism mediating reticuloendothelial system depression after surgery, Proc. Soc. Exp. Biol. Med. 133:1132.
Saba, T. M., and DiLuzio, 1969, Surgical stress and reticuloendothelial function, Surgery 65:802.
Schabel, F. M., Jr., 1969, The use of tumor growth kinetics in planning “curative” chemotherapy of advanced solid tumors, Cancer Res. 29:2384.
Schabel, F. M., Jr., 1975, Concepts for systemic treatment of micrometastases, Cancer 35:15.
Scovill, W. A., and Saba, T. M., 1973, Humoral recognition deficiency in the etiology of reticuloendothelial depression induced by surgery, Ann. Surg. 178:59.
Simpson-Herren, L., Sanford, A. H., and Holmquist, J. P., 1974, Cell. population kinetics of transplanted and metastatic Lewis lung carcinoma, Cell. Tissue Kinet. 7:349.
Skipper, H. E., 1974, Combination Therapy, p. 1, Booklet 13, Southern Research Institute, Birmingham, Ala., December 23, 1974.
Slack, N. H., Bross, E. J., Nemoto, T., and Fisher, B., 1973, Experience with bilateral primary carcinoma of the breast in a cooperative study, Surg. Gynecol. Obstet. 136:433.
Stjernswärd, J., 1968, Immune status of the primary host toward its own methylcholanthrene induced sarcomas, J. Natl. Cancer Inst. 40:13.
Urban, J. A., 1967, Bilaterality of cancer of the breast: Biopsy of the opposite breast, Cancer 20:1867.
Urban, J. A., 1969, Biopsy of the “normal” breast in treating breast cancer, Surg. Clin. N. Am. 49:291.
Valsalva, A. M., 1704, Deaure Humana Troatatus, C. Pisarii, Bononrae.
Virchow, R., 1863, Cellular Pathology, Lippincott, Philadelphia.
Ward, G. R., 1913, The blood in cancer with bone metastases, Lancet 1:676.
Watkins, S. M., 1973, The effects of surgery on lymphocyte transformation in patients with cancer, Clin. Exp. Immunol. 14:69.
Whitney, R. B., Levy, J. G., and Smith, A. G., 1974, Influence of tumor size and surgical resection on cell mediated immunity in mice, J. Natl. Cancer Inst. 53: 111.
Willis, R. A., 1953, Pathology of Tumors, 2nd ed., Butterworth, London.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1977 Plenum Press, New York
About this chapter
Cite this chapter
Fisher, B. (1977). The Changing Role of Surgery in the Treatment of Cancer. In: Becker, F.F. (eds) Radiotherapy, Surgery, and Immunotherapy. Cancer, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2739-4_10
Download citation
DOI: https://doi.org/10.1007/978-1-4684-2739-4_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-2741-7
Online ISBN: 978-1-4684-2739-4
eBook Packages: Springer Book Archive