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Herpes Simplex and Epstein-Barr Viruses in Human Cells and Tissues: A Study in Contrasts

  • Bernard Roizman
  • Elliott D. Kieff
Part of the Cancer book series (C, volume 2)

Abstract

Humans are blessed with at least five herpesviruses, i.e., herpes simplex 1 (human herpesvirus 1, HSV-1), herpes simplex 2 (human herpesvirus 2, HSV-2), herpes zoster virus (human herpesvirus 3, HZV), Epstein-Barr virus (human herpesvirus 4, EBV), cytomegalovirus (human herpesvirus 5, CMV). In recent years three of these viruses, EBV, HSV-1, HSV-2, have become prominently associated with human cancer. The purpose of this chapter is to describe briefly the biology of these three herpesviruses in human cells and tissues. The chapter is organized into four sections dealing respectively with the virion and its components, the replication of herpesviruses in permissive cells, the infection of restrictive and nonpermissive cells, with the acute diseases, latency, neoplastic diseases associated with these herpesviruses.

Keywords

Herpes Simplex Virus Herpes Simplex Virus Type Herpes Virus Burkitt Lymphoma Raji Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Bernard Roizman
    • 1
  • Elliott D. Kieff
    • 1
  1. 1.Division of Biological SciencesThe University of ChicagoChicagoUSA

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