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Dielectric Relaxation in Lipid Bilayer Membranes

  • S. Takashima
  • H. P. Schwan

Abstract

Takashima, Schwan and Tasaki(l) observed that the membrane capacitance of squid axon undergoes a dielectric relaxation in the proximity of lOKHz. They found, after careful analyses of data(vide infra) that the widely accepted membrane capacity luF/cm2 of nerve axon membrane(2) decreased to approximately 0.6 uF/cm2 between 2 and 50KHz. The origin of the frequency dependent membrane capacitance is still unknown and the present research is a further attempt to identify the component which undergoes the dispersion in the low frequency region.

Keywords

Active Element Series Resistance Dielectric Relaxation Measured Capacitance Lipid Bilayer Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. 1).
    S. Takashima, H.P. Schwan and I. Tasaki, Abstract, Annual Meeting of Biophysical Society, Paper SaAM-E2, Toronto, Canada, 1972.Google Scholar
  2. 2).
    H.P. Schwan, Advances Biol.Med.Phsics, 5, 147, 1957.Google Scholar
  3. 3).
    H.P. Schwan and T.S. Thompson, Abstract, Annual Meeting of Biophysical Soc, Paper MemB, Boston, Mass, 1966.Google Scholar
  4. 4).
    T. Hanai, D.A. Haydon and J. Taylor, Proc.Roy.Soc .London, A, 281, 377, 1964.CrossRefGoogle Scholar
  5. 5).
    S. Ohki, Biophys .J., 9, 1195, 1969.CrossRefGoogle Scholar
  6. 6).
    S. Ohki, J. Colloid and Interface Sci., 30, 413, 1969.CrossRefGoogle Scholar
  7. 7).
    S.H. White, Biophys.J., 10, 1127, 1970.CrossRefGoogle Scholar
  8. 8).
    H.G.L. Coster and R. Simmons, Biochim. Biophys. Acta, 203, 17, 1970.CrossRefGoogle Scholar
  9. 9).
    G. Stari, B. Ketterer, B. Benz and P. Lauger, Biophys.J., 11, 981, 1971.CrossRefGoogle Scholar
  10. 10).
    P. Müller and D.O. Rudin, Nature, 217, 713, 1968.CrossRefGoogle Scholar
  11. 11).
    J.L. Oncley, Protein, Amino Acids and Peptides, Ed. E.J. Cohn and J.T. Edsall, Reinhold, New York, 1943.Google Scholar
  12. 12).
    S. Takashima, Physical Principles and Techniques of Protein Chemistry, Part A, Ed. S.J. Leach, Academic Press, N.Y.1969.Google Scholar
  13. 13).
    J. Wyman, Biophysical Chemistry, Vol.1, Chapter 6, Academic Press, New York, 1958.Google Scholar
  14. 14).
    S.J. Singer and G.L. Nicolson, Science, 175, 720, 1972.CrossRefGoogle Scholar
  15. 15).
    K.S. Cole, J.Gen.Physiology, 12, 29, 1928.CrossRefGoogle Scholar
  16. 16).
    K. S. Cole, J.Gen.Physiology, 12, 37, 1928.CrossRefGoogle Scholar
  17. 17).
    K.S. Cole, Membranes, Ions and Impulses, University of California Press, Berkeley, 1968.Google Scholar
  18. 18).
    A.L. Hodgkin and A.F. Huxley, J. Physiology, 117, 500, 1952b.Google Scholar
  19. 19).
    B. Majer, Thesis, University of Pennsylvania, 1973.Google Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • S. Takashima
    • 1
  • H. P. Schwan
    • 1
  1. 1.Department of Bioengineering, Moore School of Electrical EngineeringUniversity of PennsylvaniaPhiladelphiaUSA

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