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Turnover of Plasma Proteins

  • A. S. Tavill
  • R. Hoffenberg

Abstract

The term “turnover” is used in mammalian protein metabolism to convey the concept of continuous synthesis and degradation of body proteins. Plasma proteins are, by definition, secreted into the intravascular compartment and are later distributed in other body fluid compartments in close contact with the plasma pool. They may become attached to the plasma membranes of other tissues either in the process of degradation or as part of their functional activity, and their subsequent presence within the cytoplasm of these cells may also signify uptake during catabolism, although it has been argued that physiological uptake and release from cells may also occur as part of the functional role of the protein (e.g., transferrin1).

Keywords

Plasma Protein Pool Size Synthesis Rate Specific Radioactivity Total Iron Binding Capacity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • A. S. Tavill
    • 1
  • R. Hoffenberg
    • 2
  1. 1.Clinical Research CentreHarrow, MiddlesexUK
  2. 2.Department of MedicineUniversity of BirminghamBirminghamUK

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