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Experimental Allergic Encephalomyelitis

  • Chapter
Biology of Brain Dysfunction

Abstract

This chapter is a series of discussions based on research in experimental demyelination. The discussions more or less follow the development of research on experimental allergic encephalomyelitis (EAE) as it evolved from our studies and those of others in the field. It began quite simply with the desire to clarify the etiology and pathogenesis of EAE; it appeared that this information was not only necessary but would be sufficient to permit the more difficult analysis of the etiology and pathogenesis of the human illness, multiple sclerosis. Although we were not committed to the thesis that the two diseases were one and the same entity, it seemed to us that they must share some basic mechanism.

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Authors and Affiliations

  1. Section on Myelin Chemistry, Laboratory of Cerebral Metabolism, National Institute of Mental Health, Bethesda, Maryland, USA

    Marian W. Kies

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  1. New York State Institute for Basic Research in Mental Retardation, Staten Island, New York, USA

    Gerald E. Gaull

  2. Mount Sinai School of Medicine, City University of New York, New York, New York, USA

    Gerald E. Gaull

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Kies, M.W. (1973). Experimental Allergic Encephalomyelitis. In: Gaull, G.E. (eds) Biology of Brain Dysfunction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2670-0_5

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