Jaundice pp 135-157 | Cite as

Total Body Handling of Bilirubin

  • Paul D. Berk
Part of the Hepatology book series (H, volume 2)


In a symposium at which Professor Rudi Schmid has given an elegant overview of bilirubin metabolism, and at which each individual step in the production and disposition of bilirubin has been or will be the subject of a detailed presentation by an equally distinguished expert, I am at somewhat of a loss as to the proper content of a talk covering “Total Body Handling of Bilirubin”. I believe it may be most helpful if I introduce the concept of clearance, already familiar to you in the context of renal disease, and indicate the value of measurements of bilirubin clearance in the evaluation of the patient with hyperbilirubinemia.


Bilirubin Concentration Compartmental Analysis Unconjugated Bilirubin Plasma Bilirubin Disappearance Curve 
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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Paul D. Berk
    • 1
  1. 1.National Institute of Arthritis, Metabolism and Digestive DiseasesNational Institutes of HealthBethesdaUSA

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