Hemolysis, Jaundice and Liver Disease
Jaundice due to elevation of serum unconjugated bilirubin only becomes evident when hemolytic anemia causes a two to threefold or greater increase in hemoglobin catabolism. Even in rapid hemolysis, in which the production of bilirubin from hemoglobin reaches the maximum that can be handled of about six tijnes the normal rate in an adult of 7.5 grams of hemoglobin per day, the serum level of unconjugated bilirubin rarely rises above 3 to 5 milligrams per 100 ml (Powell, 1972).
KeywordsHemolytic Anemia Obstructive Jaundice Free Cholesterol Osmotic Fragility Lithocholic Acid
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