Canalicular Anion Transport, Pathogenetic Mechanisms and a Steady State Distributed Model for Measuring Kinetics
The purposes of this review are two-fold: 1) to present a brief overview of organic anion transport at the canalicular boundary of liver cells, emphasizing the kinds of mechanisms which might be important in the pathogenesis of defective anion transport, 2) To point out the importance of standing intralobular concentration profiles to the measurement of transport kinetics at this locus and to present a distributed model which takes this difficulty into account.
KeywordsBile Salt Organic Anion Bile Flow Anion Transport Organic Anion Transport
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