Development and aging at the molecular level
The poet Wordsworth tells us that “the Child is father of the Man,” an aphorism fittingly descriptive of the continuum of growth, development and aging in which each part of the sequence is a prelude to the next stage. In this Interdisciplinary Symposium in the series on development and aging, we examine molecular and biochemical mechanisms involved in these processes at two important periods of the life of the mammal. First, changes in metabolic control are discussed in relation to the perinatal period. Second, molecular and biochemical changes are examined during the terminal period of the natural life-span of the mammal. The data gathered at these two periods of life serve to illustrate that control mechanisms encoded in the genome of the fertilized ovum continue to undergo change throughout the whole life-span of the organism.
KeywordsPerinatal Period Federation Proc Copper Metabolism Suckling Period Type Liver
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