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Radioiodinated Estrogens and Antiestrogens as Potential Imaging Agents

  • R. E. Counsell
  • A. Buswink
  • N. Korn
  • M. Johnson
  • V. Ranade
  • T. Yu
Part of the Current Topics in Molecular Endocrinology book series (CTME, volume 4)

Abstract

In an earlier chapter, Dr. William McGuire reviewed studies demonstrating that estradiol is selectively taken up by certain mammary tumors in addition to other target tissues such as uterus and pituitary. It has been our goal for the past ten years to synthesize an agent labelled with a gamma-emitting nuclide that would mimic estradiol in this selective uptake process. Theoretically, such an agent would be a useful diagnostic agent in Nuclear Medicine for the imaging of estrogen responsive tissues and tumors.

Keywords

Isotope Exchange Blood Ratio Estrogen Receptor Protein Early Chapter Nonsteroidal Estrogen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. E. Counsell
    • 1
  • A. Buswink
    • 1
  • N. Korn
    • 1
  • M. Johnson
    • 1
  • V. Ranade
    • 1
  • T. Yu
    • 1
  1. 1.Laboratory of Medicinal Chemistry, College of PharmacyUniversity of MichiganAnn ArborUSA

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