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In Vivo Methods for Studying the Action of Hypothalamic Hormones with Special Reference to Their Antisera as Tools for Investigation

  • Akira Arimura
Part of the Current topics in Molecular Endocrinology book series (CTME, volume 3)

Abstract

Physiological actions of the hypothalamic hypophysiotropic hormones were extensively studied before these hormones were isolated. Experiments were performed using crude extracts of hypothalamic tissue in order to understand the action of a hypothalamic hormone. The physiological role of a hypothalamic hormone was indirectly studied by suppressing or stimulating production or release of the hormone by making a lesion or stimulating a certain area in the brain. To learn its biokinetics, the content of the hypothalamic hormone under various conditions was measured by using bioassays. The e-normous amount of data thus accumulated by many investigators has greatly contributed to our knowledge of neuroendocrinology.

Keywords

Estrous Cycle Viable Fetus Hypothalamic Hormone Estrogen Secretion Normal Sheep Serum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Akira Arimura
    • 1
  1. 1.Veterans Administration HospitalTulane University School of MedicineNew OrleansUSA

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