Studies on the Correlation between Androgen Binding and Activation of Rat Epididymal Tubules in Culture

  • Jorge A. Blaquier
  • Monica S. Cameo
  • Ricardo Calandra
Part of the Current Topics in Molecular Endocrinology book series (CTME, volume 1)


We have recently reported that rat epididymal tissues maintained in organ culture responded to androgens added to the culture media by stimulating the incorporation of radioactive amino acids into protein (1). Similarly, the incorporation of radioactive uridine into RNA was also increased. However, in contrast to the rapid effects induced by androgens when injected into animals, the response of cultured tissues to added hormone occurred after a rather prolonged time lag.


Fetal Calf Serum Cyproterone Acetate Amino Acid Incorporation Androgen Binding Cytoplasmic Receptor 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Jorge A. Blaquier
    • 1
    • 2
  • Monica S. Cameo
    • 1
    • 2
  • Ricardo Calandra
    • 1
    • 2
  1. 1.The Population CouncilThe Rockefeller UniversityNew YorkUSA
  2. 2.Laboratorio de EsteroidesInstituto de Biologia y Medicina ExperimentalBuenos AiresArgentina

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