Properties of Rat Testicular Androgen Binding Proteins

  • Barbara M. Sanborn
  • John S. H. Elkington
  • Emil Steinberger
Part of the Current Topics in Molecular Endocrinology book series (CTME, volume 1)


The rat testis is highly dependent on gonadotropins for its function (1). Specifically, LH has been shown to be responsible for the stimulus to produce testosterone (2, 3, 4), presumably in Leydig cells, while FSH has been implicated in the maintenance of the germinal epithelium and in the later stages of spermiogenesis (1). In addition, testosterone (or a metabolite thereof) appears to have a direct role in spermatogenesis (1).


Scatchard Plot Cyproterone Acetate Germinal Epithelium Free Hormone Endogenous Testosterone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Steinberger, E., Physiol. Rev. 51, 1, 1971.Google Scholar
  2. 2.
    Greep, R. O., and Fevold, H. L., Endocrinology 21, 611, 1937.Google Scholar
  3. 3.
    Dufau, M. L., Catt, K. J., and Tsuruhara, T., Biochim. Biophys. Acta 252, 574, 1971.CrossRefGoogle Scholar
  4. 4.
    Rommerts, F. F. G., Cooke, B. A., van der Kemp, J.W. C. M., and van der Molen, H. J., FEBS Letters 33, 114, 1973.PubMedCrossRefGoogle Scholar
  5. 5.
    Means, A. R., and Vaitukaitis, J., Endocrinology 90, 39, 1972.PubMedCrossRefGoogle Scholar
  6. 6.
    Mainwaring, W. I. P,., Mangan, F. R., Wilce, P. A., and Milroy, E. G. P., In O’Malley, B. W., and Means, A. R. (eds.), Receptors for Reproductive Hormones, Plenum Press, New York, 1973, pp. 197–231.Google Scholar
  7. 7.
    Williams-Ashman, H. G., and Reddi, A. H., Ann. Rev. Physiol. Rev. 33, 31, 1971.CrossRefGoogle Scholar
  8. 8.
    Hansson, V., Djoseland, O., Reusch, E., Attramadal, A., and Torgersen, O., Steroids 21, 457, 1973.PubMedCrossRefGoogle Scholar
  9. 9.
    Ritzen, E. M., Dobbins, M. C., Tindall, D. J., French, F. S., and Nayfeh, S. N., Steroids 21, 593, 1973.PubMedCrossRefGoogle Scholar
  10. 10.
    French, F. S., and Ritzen, E. M., Endocrinology 93, 88, 1973.PubMedCrossRefGoogle Scholar
  11. 11.
    French, F. S., and Ritzen, E. M., J. Reprod. Fert. 32, 479, 1973.CrossRefGoogle Scholar
  12. 12.
    Hansson, V., Reusch, E., Trygstd, O., Torgersen, O., Ritzen, E. M., and French, F. S., Nature New Biol. 246, 56, 1973.PubMedGoogle Scholar
  13. 13.
    Layne, E., Methods. Enzymol. 111, 448, 1957.Google Scholar
  14. 14.
    Scatchard, G., Ann. N. Y. Acad. Sci. USA 51, 660, 1949.CrossRefGoogle Scholar
  15. 15.
    Tanford, C., Physical Chemistry of Macromolecules, J. Wiley & Sons, Inc., New York, 1961, pp. 573–574.Google Scholar
  16. 16.
    Milgrom, E., Perrot, M., Atger, M., and Baulieu, E.E., Endocrinology 90, 1064, 1972.PubMedCrossRefGoogle Scholar
  17. 17.
    Sanborn, B. M., Elkington, J. S. H., Tcholakian, R. K., Chowdhury, M., and Steinberger, E., unpublished, 1974.Google Scholar
  18. 18.
    Ritzen, E. M, Nayfeh, S. N., French, F. S., and Dobbins, M. C., Endocrinology 89, 143, 1971.PubMedCrossRefGoogle Scholar
  19. 19.
    Hansson, V., Djoseland, O., Reusch, E., Attramadal, A., and Torgersen, O., Steroids 22, 19, 1973.PubMedCrossRefGoogle Scholar
  20. 20.
    Danzo, B. J., Orgebin-Crist, M. -C., and Toft, D. O., Endocrinology 92, 310, 1973.PubMedCrossRefGoogle Scholar
  21. 21.
    Sanborn, B. M., Elkington, J. S. H., and Steinberger, E. M., unpublished, 1973.Google Scholar
  22. Vernon, R. G., Kopec, B., and Fritz, I. B., J. Endocr. 57, 11, 1973.Google Scholar
  23. 23.
    Frost, A. A., and Pearson, R. G., Kinetics and Mechanism, J. Wiley & Sons, New York, 1961, p. 162.Google Scholar
  24. 24.
    Davis, B. J., Ann. N. Y. Acad. Sci. USA 121, 404, 1964.CrossRefGoogle Scholar
  25. 25.
    Korenman, S. G., Endocrinology 87, 1119, 1970.CrossRefGoogle Scholar
  26. 26.
    Vernon, R. G., Dorrington, J. H., and Fritz, I. B., IV Int. Cong. Endocrinol. Abstr. 200, Washington, D. C., June 1972.Google Scholar
  27. 27.
    Hansson, V., Ritzen, E. M., French, F. S., Weddington, S. C., Nayfeh, S. N., Reusch, E., and Attramadal, A., Steroids 22, 185, 1973.PubMedCrossRefGoogle Scholar
  28. 28.
    Hansson, V., Steroids 20, 575, 1972.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Barbara M. Sanborn
    • 1
  • John S. H. Elkington
    • 1
  • Emil Steinberger
    • 1
  1. 1.Program in Reproductive Biology and EndocrinologyUniversity of Texas Medical School at HoustonHoustonUSA

Personalised recommendations