Evidence for Multiple, Cell Specific, Distinctive Adenylate Cyclase Systems in Rat Testis

  • T. Braun
Part of the Current Topics in Molecular Endocrinology book series (CTME, volume 1)


Considerable evidence has been accumulated during the last decade which indicates that a large group of hormones acts through the mediation of the adenylate cyclase system in the target cell plasma membrane (1). It has been established that adenylate cyclase systems in various cell types are hormone selective, and many exhibit specific metal and/or nucleotide requirement for ‘optimal’ catalytic activity and/or for hormonal activation (2, 3). Hormone selectivity of adenylate cyclase systems in various target cells depends upon distinctive receptors which ‘recognize’ and interact with the hormone in a specific binding reaction which leads to adenylate cyclase activation and cyclic AMP (cAMP) generation.


Adenylate Cyclase Sertoli Cell Cell Fraction Seminiferous Tubule Guanylate Cyclase 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • T. Braun
    • 1
  1. 1.Department of PhysiologyNorthwestern University Medical CenterChicagoUSA

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