Binding of Human FSH and Its Subunits to Rat Testis
It has long been recognized that for a hormone to activate a target tissue, it must bind to some element of the cell. Roth and his colleagues (1) and Goodfriend and Lin (2) introduced appropriate techniques for directly studying the binding of a hormone to its target cell. Catt, Dufau and their colleagues (3, 4) and Reichert et al. (5) have characterized the binding of labeled human Luteinizing Hormone (hLH) and of human Chorionic Gonadotropin (hCG) to rat testis in vitro and impressive advances have been made in the isolation of the specific receptor hCG.
KeywordsChorionic Gonadotropin Testicular Tissue Tissue Fraction Sodium Metabisulfite Testicular Receptor
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