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Attempts to Correct Age-Related Immunodeficiency and Autoimmunity by Cellular and Dietary Manipulation in Inbred Mice

  • Gabriel Fernandes
  • Robert A. Good
  • Edmond J. Yunis
Part of the Comprehensive Immunology book series (COMIMUN, volume 1)

Abstract

The association of immunologic malfunction with aging has been viewed in several ways. The immunologic theory of aging, first clearly stated by Walford (1969), has been extensively promulgated by Burnet (1970b). This theory states that the immune system is essential to maintenance of health and that, to a major extent, the integrity of the immune system determines survival. Further, Walford has maintained that the immune system is involved in the pathogenesis of many of the diseases that occur in aging man and animals and may actually be involved in the pathogenesis of the aging process itself.

Keywords

Spleen Cell Dietary Manipulation Young Donor Autoimmune Phenomenon Thymus Transplant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • Gabriel Fernandes
    • 1
  • Robert A. Good
    • 2
  • Edmond J. Yunis
    • 1
  1. 1.Department of Laboratory Medicine and PathologyUniversity of MinnesotaMinneapolisUSA
  2. 2.Sloan-Kettering Institute for Cancer ResearchNew YorkUSA

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