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Visceral Learning: Cardiovascular Conditioning in Primates

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Biofeedback and Behavior

Part of the book series: NATO Conference Series ((HF,volume 2))

Abstract

Behavior science developments over the past decade (Honig & Staddon, 1976), coupled with rapid advances in techniques for monitoring the circulation (Obrist, Black, Brener, & DiCara, 1974) have contributed substantially to the systematic experimental analysis of interacting cardiovascular-behavioral processes which define psychophysiological aspects of stress, anxiety, and emotional arousal. The results of rapidly expanding laboratory investigative efforts in this complex domain appear to reflect the emergence of two general models for the experimental analysis of such psychophysiological relationships (Brady & Harris, 1976). The first and more traditional concurrent model emphasizes the effects of antecedent or concurrent behavioral interactions upon the elicitation of physiological responses and has provided a productive framework for laboratory studies since at least the time of Pavlov (1879) and Cannon (1929). The second and more contemporary contingent model, in contrast, focuses upon the controlling effects of environmental-behavioral consequences which follow such physiological changes and bear a close temporal relationship to their occurrence.

“The importance of feed-back is clear. The organism must be stimulated by the consequences of its behavior if conditioning is to take place. In learning to wiggle one’s ears, for example, it is necessary to know when the ears move if responses which produce movement are to be strengthened in comparison with responses which do not. In re-educating the patient in the use of a partially paralyzed limb, it may be of help to amplify the feed-back from slight movements, either with instruments or through the report of an instructor.”

(Skinner, 1953).

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References

  • Anderson, D. E., & Brady, J. V., Preavoidance blood pressure eleva- tions accompanied by heart rate decreases in the dog. Science, 1971, 172, 595–597.

    Article  PubMed  Google Scholar 

  • Anderson, D. E., & Brady, J. V., Differential preparatory cardiovascular responses to aversive and appetitive behavioral conditioning. Conditional Reflex, 1972, 7, 82–96.

    PubMed  Google Scholar 

  • Anderson, D. E., & Brady, J. V., Effects of beta blockade on cardiovascular responses to avoidance performance in dogs. Psychosomatic Medicine, 1973, 35, 457.

    Google Scholar 

  • Anderson, D. E., Yingling, J., & Brady, J. V., Effects of alpha adrenergic blockade upon cardiovascular responses of the dog to avoidance contingencies. Pavlovian Journal of Biological Science, 1975, 9, 173.

    Google Scholar 

  • Ahlquist, R. P., A study of the adrenotropic receptors. American Journal of Physiology, 1948, 153, 585–600.

    Google Scholar 

  • Axelrod, J., Mueller, R. A., Henry, J. P., et al. Changes in enzymes involved in the biosynthesis and metabolism of noradrenaline and adrenaline after psychosocial stimulation. Nature (London), 1970, 225, 1059–1060.

    Article  Google Scholar 

  • Benson, H., Herd, J. A., Morse, W. H., & Kelleher, R. T., Behavioral inductions of arterial hypertension and its reversal. American Journal of Physiology, 1969, 217, 30–34.

    PubMed  Google Scholar 

  • Benson, H., Shapiro, D., Tursky, B., & Schwartz, G. E., Decreased systolic blood pressure through operant conditioning techniques in patients with essential hypertension. Science, 1971, 173, 740.

    Article  PubMed  Google Scholar 

  • Bergamaschi, M., & Longoni, A. M., Cardiovascular events in anxiety: Experimental studies in the conscious dog. American Heart Journal, 1973, 86, 385–394.

    Google Scholar 

  • Birk, L., (Ed.) Biofeedback: Behavioral medicine. New York: Grune & Stratton, 1973.

    Google Scholar 

  • Brady, J. V., Endocrine and autonomic correlates of emotional behavior. In P. Black (Ed.), Physiological correlates of emotion. New York: Academic Press, 1970.

    Google Scholar 

  • Brady, J. V., & Harris, A. H., The experimental production of altered physiological states: Concurrent and contingent behavioral models. In W. Honig & J. E. R. Staddon (Eds.), Handbook of operant behavior. New York: Prentice-Hall, in press.

    Google Scholar 

  • Brady, J. V., Kelly, D., & Plumlee, L., Autonomic and behavioral responses of the rhesus monkey to emotional conditioning. Annals of the New York Academy of Science, 1969, 159, 959–975.

    Article  Google Scholar 

  • Brod, J., Fenel, V., Hejl, Z., & Jirka, J., Circulatory changes underlying blood pressure elevation during acute emotional stress (mental arithmetic) in normotensive and hypertensive subjects. Clinical Science, 1959, 18, 269.

    PubMed  Google Scholar 

  • Cannon, W. B., Bodily changes in pain, fear, hunger and rage ( 2nd ed. ). New York: Appleton-Century-Crofts, 1929.

    Google Scholar 

  • Cannon, W. B., & De La Paz, D., Emotional stimulation of adrenal secretion. American Journal of Physiology, 1911, 27, 64.

    Google Scholar 

  • Charvat, J., Dell, P., & Folkow, B., Mental factors in cardiovascular disease. Cardiologia, 1964, 44, 121.

    Article  Google Scholar 

  • Dews, P. B., & Herd, J. A., Behavioral activities and cardiovascular functions: Effects of hexamethonium on cardiovascular changes during strong sustained static work in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 1974, 189, 12–23.

    PubMed  Google Scholar 

  • DiCara, L. V., Learning in the autonomic nervous system. Scientific American, 1970, 222 (1), 30–39.

    Article  PubMed  Google Scholar 

  • DiCara, L., & Miller, N. E., Instrumental learning of vasomotor responses by rats: Learning to respond differentially in the two ears. Science, 1968, 159, 1485–1486.

    Google Scholar 

  • DiCara, L., & Miller, N. E., Changes in heart rate instrumentally learned by curarized rats as avoidance responses. Journal of Comparative and Physiological Psychology, 1968, 65, 1–7.

    Article  Google Scholar 

  • Eich, R. H., Cuddy, R. P., Smulyan, H., & Lyons, R. H., Hemodynamics in labile hypertension: A follow-up study. Circulation, 1966, 34, 299.

    Google Scholar 

  • Eich, R. H., Peters, R. J., Cuddy, R. P., Smulyan, H. I., & Lyons, R. H., Hemodynamics in labile hypertension. American Heart Journal, 1962, 63, 188.

    Article  PubMed  Google Scholar 

  • Engelman, K., & Braunwald, E., Hypotension and the shock syndrome. In M. M. Wintrobe, G. W. Thorn, R. D. Adams, E. Braunwald, K. J. Isselbacher, & R. G. Petersdorf (Eds.), Harrison’s principles of internal medicine. New York: McGraw-Hill, 1974.

    Google Scholar 

  • Engel, B. T., & Gottlieb, S. H., Differential operant conditioning of heart rate in the restrained monkey. Journal of Comparative and Physiological Psychology, 1970, 73 (2), 217–225.

    Article  PubMed  Google Scholar 

  • Engel, B. T., & Melmon, K. L., Operant conditioning of heart rate in patients with cardiac arrhythmias. Conditioned Reflex, 1968, 3, 130.

    Google Scholar 

  • Fields, C., Instrumental conditioning of the rat cardiac control systems. Proceedings of the National Academy of Sciences, 1970, 65 (2), 293–299.

    Article  Google Scholar 

  • Findley, J. D., Brady, J. V., Robinson, W. W., & Gilliam, W. J., Continuous cardiovascular monitoring in the baboon during long-term behavioral performances. Communications in Behavioral Biology, 1971, 6, 49–58.

    Google Scholar 

  • Findley, J. D., Robinson, W. W., & Gilliam, W. J., A restraint system for chronic study of the baboon. Journal of the Experimental Analysis of Behavior, 1971, 15, 69–71.

    Article  PubMed  Google Scholar 

  • Finkielman, S., Worcel, M., & Agrest, A., Hemodynamic patterns in essential hypertension. Circulation, 1965, 31, 356–368.

    PubMed  Google Scholar 

  • Folkow, B., & Rubinstein, E. H., Cardiovascular effects of acute and chronic stimulations of the hypothalamic defense area in the rat. Acta Physiologica Scandinavia, 1966, 68, 48.

    Article  Google Scholar 

  • Forsyth, R. P., Blood pressure and avoidance conditioning. Psychosomatic Medicine, 1968, 39 (1), 125–138.

    Google Scholar 

  • Forsyth, R. P., Blood pressure responses to long-term avoidance schedules in the restrained rhesus monkey. Psychosomatic Medicine, 1969, 31, 300–309.

    PubMed  Google Scholar 

  • Forsyth, R. P., Regional blood-flow changes during 72-hour avoidance schedules in the monkey. Science, 1971, 173, 546–548.

    Article  PubMed  Google Scholar 

  • Forsyth, R. P., Sympathetic nervous system control of distribution of cardiac output in unanesthetized monkeys. Federation Proceedings, 1972, 31 (4), 1240–1244.

    PubMed  Google Scholar 

  • Forsyth, R. P., & Harris, R. E., Circulatory changes during stressful stimuli in rhesus monkeys. Circulation Research, 1970, 27 (Suppl.), 1–13.

    Google Scholar 

  • Forsyth, R. P., Hoffbrand, B. I., & Melmon, K. L., Hemodynamic effects of angiotensin in normal and environmentally stressed monkeys. Circulation, 1971, 44, 119–129.

    PubMed  Google Scholar 

  • Forsyth, R. P., & Rosenblum, M. A., A restraining device and procedure for continuous blood pressure recordings in monkeys. Journal of the Experimental Analysis of Behavior, 1964, 7 (5), 367–368.

    Article  PubMed  Google Scholar 

  • Frankenhaeuser, M., Behavior and circulating catecholamines. Brain Research, 1971, 31, 241–262.

    Article  PubMed  Google Scholar 

  • Frohlich, E. D., Kozul, V. J., Tarazi, R. C., & Dunstan, H. P., Physiological comparison of labile and essential hypertension. Circulation Research, 1970 (Suppl. 1), 26 & 27, 1–55.

    Google Scholar 

  • Goodman, L. S., & Gilman, A., The pharmacological basis of therapeutics. New York: Macmillan, 1970.

    Google Scholar 

  • Harris, A. H., & Brady, J. V., Animal learning: Visceral and autonomic conditioning. Annual Review of Psychology, 1974, 25, 107–133.

    Article  PubMed  Google Scholar 

  • Harris, A. H., & Brady, J. V., Long-term studies of cardiovascular control in primates. In G. E. Schwartz & J. Beatty, (Eds.), Biofeedback: Theory and research. San Francisco: Academic Press, 1976, in press.

    Google Scholar 

  • Harris, A. H., Findley, J. D., & Brady, J. V., Instrumental conditioning of blood pressure elevations in the baboon. Conditioned Reflex, 1971, 6, 215–226.

    Google Scholar 

  • Harris, A. H., Gilliam, W. J., & Brady, J. V., Operant conditioning of heart rate in the baboon. Pavlovian Journal of Biological Science, 1976, in press.

    Google Scholar 

  • Harris, A. H., Gilliam, W. J., Findley, J. D., & Brady, J. V., Instrumental conditioning of large magnitude daily 12-hour blood pressure elevations in the baboon. Science, 1973, 183, 175.

    Article  Google Scholar 

  • Henry, J. P., & Cassel, J. C., Psychosocial factors in essential hyper- tension. American Journal of Epidemiology, 1969, 90, 171.

    PubMed  Google Scholar 

  • Henry, J. P., Stephens, P. M., Axelrod, J., & Mueller, R. A., Effect of psychosocial stimulation on the enzymes involved in the biosynthesis and metabolism of noradrenaline and adrenaline. Psychosomatic Medicine, 1971, 33, 227–237.

    PubMed  Google Scholar 

  • Herd, J. A., Morse, W. H., Kelleher, R. T., & Jones, L. G., Arterial hypertension in the squirrel monkey during behavioral experiments. American Journal of Physiology, 1969, 217, 24–29.

    PubMed  Google Scholar 

  • Higgins, C. B., Vatner, S. F., & Braunwald, E., Parasympathetic control of the heart. Pharmacological Reviews, 1973, 25, 119–155.

    PubMed  Google Scholar 

  • Honig, W., & Staddon, J. E. R., (Eds.) Handbook of operant behavior. New York: Prentice-Hall, 1976, in press.

    Google Scholar 

  • Julius, S., & Conway, J., Hemodynamic studies in patients with borderline blood pressure elevation. Circulation, 1968, 38, 282–288.

    PubMed  Google Scholar 

  • Katkin, E. S., & Murray, E. N., Instrumental conditioning of autonomically mediated behavior: Theoretical and methodological issues. Psychological Bulletin, 1968, 70, 52–68.

    Google Scholar 

  • Kelleher, R. T., Morse, W. H., & Herd, J. A., Effects of propranolol, phentolamine, and methyl atropine on cardiovascular functions in the squirrel monkey during behavioral experiments. The Journal of Pharmacology and Experimental Therapeutics, 1972, 183, 204–217.

    Google Scholar 

  • Klose, K. J., Augenstein, J. S., Schneiderman, N., Manas, K., Abrams, B., & Bloom, L. J., Selective autonomic blockade of conditioned and unconditioned cardiovascular changes in rhesus monkeys (Macaca mulatta). Journal of Comparative and Physiological Psychology, 1975, 89, 810–818.

    Article  PubMed  Google Scholar 

  • Korner, P. I., Integrative neural cardiovascular control. Physiological Reviews, 1971, 51, 312–367.

    PubMed  Google Scholar 

  • Luetscher, J. A., Boyers, D. G., Cuthbertson, J. C., & McMahon, D. F., A model of the human circulation. Circulation Research, 1973, Suppl. Ito Vols. 32–33, I-84 - I - 97.

    Google Scholar 

  • Mason, J. W., et al. Organization of psychoendocrine mechanisms. Psychosomatic Medicine, 1968, 30, 565–808.

    PubMed  Google Scholar 

  • McCubbin, J. W., DeMoura, R. S., Page, I. H., & Olmsted, F., Arterial hypertension elicited by subpressor amounts of angiotensin. Science, 1966, 149, 1394.

    Article  Google Scholar 

  • McCutcheon, E. P., (Ed.) Chronically implanted cardiovascular instrumentation. New York: Academic Press, 1973.

    Google Scholar 

  • McGraw, A. P., & Sim, A. K., Clinical biochemistry of the baboon. Journal of Comparative Pathology, 1973, 82, 193.

    Article  Google Scholar 

  • Miller, N. E., Learning of visceral and glandular responses. Science, 1969, 163, 434–445.

    Article  PubMed  Google Scholar 

  • Miller, N. E., & Banuazizi, A., Instrumental learning by curarized rats of a specific visceral response, intestinal or cardiac. Journal of Comparative and Physiological Psychology, 1968, 65, 1–7.

    Article  PubMed  Google Scholar 

  • Miller, N. E., & DiCara, L., Instrumental learning of heart rate changes in curarized rats: Shaping and specificity to discriminative stimulus. Journal of Comparative and Physiological Psychology, 1967, 63, 12–19.

    Article  PubMed  Google Scholar 

  • Nathan, M. S., & Smith, O. A., Jr., Differential conditional emotional and cardiovascular responses–A training technique for monkeys. Journal of the Experimental Analysis of Behavior, 1968, 11, 77–82.

    Article  PubMed  Google Scholar 

  • Nickerson, M., Adrenergic receptors. Circulation Research, 1973, Suppl. I to Vols. 32–33, I-53 - I - 59.

    Google Scholar 

  • Obrist, P. A., Black, A. H., Brener, J., & DiCara, L. V., (Eds.) Cardiovascular psychophysiology. Chicago: Aldine, 1974.

    Google Scholar 

  • Page, I. H., & McCubbin, J. W., Renal hypertension. Chicago: Yearbook Medical Publishers, 1968.

    Google Scholar 

  • Pavlov, I. P., Uber die normalen. blutdruckshwanjungen beim hunde. Archiv Fur die Gesampte Physiologie des Menschen und der Tiere, 1879, 20, 215.

    Article  Google Scholar 

  • Pickering, G. W., The nature of essential hypertension. London: J & A Churchill, 1961.

    Google Scholar 

  • Plumlee, L. A., Operant conditioning of blood pressure increases and decreases in the monkey. Psychophysiology, 1968, 4, 507.

    Google Scholar 

  • Plumlee, L. A., Operant conditioning of increases in blood pressure. Psychophysiology, 1969, 6, 283–290.

    Article  PubMed  Google Scholar 

  • Randall, D. C., & Smith, O. A., Jr., Ventricular contractility during controlled exercise and emotion in the primate. American Journal of Physiology, 1974, 226, 1951–1959.

    Google Scholar 

  • Saslow, G., & Blackly, P. H., Introduction. In Timberline Conference on Psychophysiologic Aspects of Cardiovascular Disease. Psychosomatic Medicine, 1964, 26, 409.

    PubMed  Google Scholar 

  • Schwartz, G. E., Shapiro, D., & Tursky, B., Learned control of cardiovascular integration in man through operant conditioning. Psychosomatic Medicine, 1971, 33, 57–62.

    PubMed  Google Scholar 

  • Shapiro, D., Schwartz, G. E., & Tursky, B., Control of diastolic blood pressure in man by feedback and reinforcement. Psychophysiology, 1971, 8, 262.

    Google Scholar 

  • Shapiro, D., Tursky, B., & Gerson, E., Effects of feedback and reinforcement on the control of human systolic blood pressure. Science, 1969, 163, 588.

    Article  PubMed  Google Scholar 

  • Shapiro, D., Tursky, B., & Schwartz, G., Control of blood pressure in man by operant conditioning. Circulation Research, 1970 (Suppl. 1), 26 & 27, 1.

    Google Scholar 

  • Sidman, M., Avoidance conditioning with brief shock and no exteroceptive warning signal. Science, 1953, 118, 157–158.

    Article  PubMed  Google Scholar 

  • Skinner, B. F., Science and human behavior. New York: Macmillan, 1953.

    Google Scholar 

  • Stephens, J., Harris, A. H., & Brady, J. V., Large magnitude heart rate changes in subjects instructed to change their heart rates and given exteroceptive feedback. Psychophysiology, 1972, 9, 283–285.

    Article  PubMed  Google Scholar 

  • Swinnen, M. E. T., Blood pressure digitizer. Proceedings Annual Conference Engineering in Medicine and Biology, 1968, 10, 18. 4.

    Google Scholar 

  • Varma, S., Johnson, S. D., Sherman, D. E., & Youmans, M. D., Mechanisms of inhibition of heart rate by phenylephrine. Circulation Research, 1960, 8, 1182–1186.

    PubMed  Google Scholar 

  • Weber, H. W., Brede, H. D., Retief, F. P., & Melby, E. C., Jr., The baboon in medical research: Baseline studies in fourteen hundred baboons and pathological observations. Defining the laboratory animal, National Academy of Science, Washington, D. C., 1971.

    Google Scholar 

  • Weiss, T., & Engel, B. T., Operant conditioning of heart rate in patients with premature ventricular contractions. Psychosomatic Medicine, 1971, 33, 301–321.

    PubMed  Google Scholar 

  • Werdegar, D., Johnson, D. G., & Mason, J. W., A technique for continuous measurement of arterial blood pressure in unanesthetized monkeys. Journal of Applied Physiology, 1964, 19, 519.

    PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Division of Behavioral Biology Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, USA

    Alan H. Harris, David S. Goldstein & Joseph V. Brady

Authors
  1. Alan H. Harris
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  2. David S. Goldstein
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  3. Joseph V. Brady
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Editor information

Editors and Affiliations

  1. University of California, Los Angeles, California, USA

    Jackson Beatty

  2. Max Planck Institut für Psychiatrie, Munich, Federal Republic of Germany

    Heiner Legewie

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© 1977 Plenum Press, New York

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Harris, A.H., Goldstein, D.S., Brady, J.V. (1977). Visceral Learning: Cardiovascular Conditioning in Primates. In: Beatty, J., Legewie, H. (eds) Biofeedback and Behavior. NATO Conference Series, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2526-0_13

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  • DOI: https://doi.org/10.1007/978-1-4684-2526-0_13

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