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Jejunal Viral Antigen in Multiple Sclerosis and Amyotrophic Lateral Sclerosis

  • Albert W. Cook
  • Louis P. Pertschuk
  • Jagdish K. Gupta
  • Dong S. Kim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 100)

Abstract

Statistical data is presented regarding the identification of viral antigen in the jejunum of patients with multiple sclerosis (MS) and other neurological disease, in particular amyotrophic lateral sclerosis (motor neuron disease). The viral antigens were identified using fluorescent antibody techniques previously described (1–3). Jejunal specimens were obtained by conventional passage of a small peroral tube with an attached capsule. The position of the capsule was identified radiographically to be in the proximal jejunum. In some instances, particularly in patients with amyotrophic lateral sclerosis (ALS), impairment of swallowing necessitated the use of a fiber-optic jejunoscope.

Keywords

Multiple Sclerosis Amyotrophic Lateral Sclerosis Motor Neuron Disease Jejunal Mucosa Downstate Medical 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Pertschuk, L.P., Cook, A.W. and Gupta, J., Measles antigen in multiple sclerosis: identification in the jejunum by immunofluorescence, Life Sci. 19 (1976) 1603 – 1608.PubMedCrossRefGoogle Scholar
  2. 2.
    Pertschuk, L.P., Cook, A.W., Gupta, J.K., Broome, J.D., Vuletin, J.C., Kim, D.S., Brigati, D.J., Rainford, E.A. and Nidsgorski, F., Jejunal immunopathology in amyotrophie lateral sclerosis and multiple sclerosis, Lancet I (1977) 1119 – 1123.CrossRefGoogle Scholar
  3. 3.
    Pertschuk, L.P., Cook, A.W., Gupta, J.K., Broome, J.D., Vuletin, J.C., Kim, D.S., Stanek, A.E., Brigati, D.J., Rain-ford, E.A. and Nidsgorski, F., Measles antigen in the jejunum in multiple sclerosis, Lancet II (1977) 300 – 301.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Albert W. Cook
    • 1
  • Louis P. Pertschuk
    • 2
  • Jagdish K. Gupta
    • 3
  • Dong S. Kim
    • 4
  1. 1.Department of Neuroscience, Long Island College Hospital, and Downstate Medical CenterState University of New YorkUSA
  2. 2.Downstate Medical CenterState University of New YorkUSA
  3. 3.Department of Medicine, Division of GastroenterologyLong Island College HospitalUSA
  4. 4.Downstate Medical CenterState University of New YorkBrooklynUSA

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