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New Approaches in the Management of Hyperkinetic Movement Disorders

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Parkinson’s Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 90))

Abstract

This review covers recent advances in a variety of dyskinesias. Introduction of new drugs for the treatment of myoclonus and sensory biofeedback therapy for focal dystonia are expanding our concepts of these types of movement disorders. Progress in the treatment of action myoclonus is especially noteworthy and has led to the impli cation of serotonin deficit in the pathophysiology of this syndrome. Knowledge of the biochemical pathology of Huntington’s chorea has outpaced therapy for this disorder, but new forms of therapy have been proposed based on the chemical findings. Basic pharmacologic studies suggest pathophysiologic mechanisms for the syndrome known as tardive dyskinesia, but treatment is still far from ideal for this disorder. Other movement disorders with recent therapeutic advances include essential tremor and hemiballism

This review will cover only those dyskinesias in which new therapies have been advanced in the last few years. Aside from parkinsonism, which will not be discussed here, progress in the treatment of movement disorders has been slow, but steady. New drugs are being tested constantly, and the purpose of this review is to call attention to the ongoing evaluations in this field. Descriptions and etiologies for these dyskinesias are covered elsewhere (Fahn, 1976a) and therefore are not repeated here.

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Authors and Affiliations

  1. Department of Neurology, College of Physicians and Surgeons and Neurological Institute of New York, Columbia University, New York, New York, 10032, USA

    Stanley Fahn M.D.

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  1. Stanley Fahn M.D.
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Editors and Affiliations

  1. Departments of Pharmacology and Therapeutics and Psychiatry, Texas Tech University School of Medicine, Lubbock, Texas, USA

    Fathy S. Messiha Ph. D. (Associate Professor, Chairman) (Associate Professor, Chairman)

  2. Department of Pharmacology and Therapeutics, Tarbox Parkinson’s Disease Institute, Texas Tech University School of Medicine, Lubbock, Texas, USA

    Alexander D. Kenny Ph. D. (Professor and Chairman, Acting Director) (Professor and Chairman, Acting Director)

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© 1977 Plenum Press, New York

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Fahn, S. (1977). New Approaches in the Management of Hyperkinetic Movement Disorders. In: Messiha, F.S., Kenny, A.D. (eds) Parkinson’s Disease. Advances in Experimental Medicine and Biology, vol 90. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-2511-6_7

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  • DOI: https://doi.org/10.1007/978-1-4684-2511-6_7

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  • Print ISBN: 978-1-4684-2513-0

  • Online ISBN: 978-1-4684-2511-6

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