Maternally Determined Susceptibility to D-Amphetamine-Induced Stereotypy in Rats
During the first week after parturition, rat pups were removed and returned to a mother-present nest, were removed and returned to a mother-absent nest, were separated from their mothers by removal of the mothers, or were undisturbed. In adulthood, when repeatedly injected with a dose of D-amphetamine which induces progressively higher levels of stereotypy (2.5 mg/kg), only subjects which had been removed and returned to a mother-present nest in infancy showed a retarded rate of increase in stereotypy.
KeywordsLocomotor Activity Maternal Behavior Ultrasonic Vocalization Absent Group Undisturbed Control
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