Senescence pp 81-85 | Cite as

Improved Techniques for the Fusion of Mammalian Cells

  • Richard L. Davidson
Part of the Cellular Senescence and Somatic Cell Genetics book series (CSSCG, volume 2)


As indicated by the title of this symposium “Is Senescence Dominant or Recessive in Somatic Cell Crosses”, cell fusion has become an important technique for the study of the problem of cell senescence. However, despite the widespread use of cell fusion to study cell senescence and many other areas in mammalian cell biology and genetics, the induction of cell fusion has remained a major problem. In some cases, the ability (or inability) to induce fusion has been the limiting factor in experimental programs. The purpose of this paper is to present improvements in the techniques of cell fusion, which improvements could facilitate the types of experiments described in other papers in this symposium.


Cell Fusion Sendai Virus Fusion Activity Somatic Cell Genetic Viable Hybrid 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Richard L. Davidson
    • 1
    • 2
  1. 1.Department of Microbiology and Molecular GeneticsHarvard Medical SchoolBostonUSA
  2. 2.Division of Human GeneticsChildren’s Hospital Medical CenterBostonUSA

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