Glucagon and Somatostatin

  • Roger H. Unger


The primary structure of true glucagon, the biologically active 3485-molecular-weight polypeptide, is identical in all mammalian species thus far studied, with the exception of the guinea pig. Porcine (Bromer et al., 1957), bovine (Bromer et al., 1971), and human (Thomsen et al., 1972) glucagons have identical sequences, and it is likely that rabbit (Sundby and Markussen, 1972), camel, and rat (Sundby and Markussen, 1971) glucagons are also identical. The guinea pig glucagon, however, has a molecular weight of 4000–5000 and appears to differ from porcine glucagon (Sundby, 1976).


Adenosine Pancreatitis Ketone Pyruvate Prostaglandin 
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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Roger H. Unger
    • 1
    • 2
  1. 1.Veterans Administration HospitalDallasUSA
  2. 2.Department of Internal MedicineThe University of Texas Southwestern Medical SchoolDallasUSA

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