Structural and Functional Aspects of the Superior Colliculus in Primates

  • Roberta Pierson Pentney
  • John R. Cotter
Part of the Advances in Primatology book series (AIPR)


The superior colliculus is a phylogenetically old cortex, but determination and measurement of its function in primates has proved to be a particularly difficult and challenging task. It has been known for over a century that stimulation of the colliculus produces eye movements (Adamuk, 1870), but no experimental design has yielded an adequate answer to the question of the exact functional role of the colliculus.


Receptive Field Superior Colliculus Inferior Colliculus Squirrel Monkey Tree Shrew 
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  1. Abplanalp, P. 1970. Some subcortial connections of the visual system in tree shrews and squirrels. Brain Behau. Evol. 3:155–168.CrossRefGoogle Scholar
  2. Abplanalp, P. 1971. The neuroanatomical organization of the visual system in the tree shrew. Folia Primatol. 16:1–34.PubMedCrossRefGoogle Scholar
  3. Adamuk, E. 1870. Über die Innervation der Augenbewegungen. Zbl. Med. Wiss. 8:65–67.Google Scholar
  4. Anderson, K. V., and Symmes, D. 1969. The superior colliculus and higher visual functions in the monkey. Brain Res. 13:37–52.PubMedCrossRefGoogle Scholar
  5. Benevento, L. A., and Fallon, J. H. 1975. The ascending projections of the superior colliculus in the rhesus monkey (Macaca mulatto).J. Comp. Nenrol. 160:339–362.CrossRefGoogle Scholar
  6. Campbell, C. B. G. 1969. The visual system of insectivores and primates. Ann. N.Y. Acad. Sci. 167:388–403.CrossRefGoogle Scholar
  7. Campbell, C. B. G., Jane, J. A., and Yashon, D. 1967. The retinal projections of the tree shrew and hedgehog. Brain Res. 5:406–418.PubMedCrossRefGoogle Scholar
  8. Campos-Ortega, J. A. 1968. Descending subcortical projections from the occipital lobe of Galago crassicaudatus.Exp. Nenrol. 21:440–454.CrossRefGoogle Scholar
  9. Campos-Ortega, J. A., and Cliiver, P. F. De V. 1968. The distribution of retinal fibers in Galago crassicaudatus.Brain Res. 7:487–489.PubMedCrossRefGoogle Scholar
  10. Campos-Ortega, J. A., and Glees, P. 1967a. The visual subcortical connexions in the squirrel monkey (Saimiri sciureus).J. Physiol. (London)191:93P–95P.Google Scholar
  11. Campos-Ortega, J. A., and Glees, P. 1967b. The subcortical distribution of optic fibers in Saimiri sciureus (squirrel monkey). J. Comp. Neurol. 131:131–142.PubMedCrossRefGoogle Scholar
  12. Campos-Ortega, J. A., Hayhow, W. R., and Cliiver, P. F. De V. 1970. The descending projections from the cortical visual fields of Macaca mulatta with particular reference to the question of a cortico-lateral geniculate pathway. Brain Behau. Evol. 3:368–414.CrossRefGoogle Scholar
  13. Casagrande, V. A., Harting, J. K., Hall, W. C., and Diamond, I. T. 1972. Superior colliculus of the tree shrew: A structural and functional subdivision into superficial and deep layers. Science 177:444–447.PubMedCrossRefGoogle Scholar
  14. Cynader, M., and Berman, N. 1972. Receptive-field organization of monkey superior colliculus. J. Neurophysiol. 35:187–200.PubMedGoogle Scholar
  15. Giolli, R. A., and Tigges, J. 1970. The primary optic pathways and nuclei of primates. In C. R. Noback and W. Montagna (eds.). The Primate Brain. Appleton-Century-Crofts, New York. Pp. 29–54.Google Scholar
  16. Goldberg, M. E., and Wurtz, R. H. 1972a. Activity of superior colliculus in behaving monkey. I. Visual receptive fields of single neurons. J. Neurophysiol. 35:542–559.PubMedGoogle Scholar
  17. Goldberg, M. E., and Wurtz, R. H. 1972b. Activity of superior colliculus in behaving monkey. II. Effects of attention on neuronal responses. J. Neurophysiol. 35:560–574.PubMedGoogle Scholar
  18. Goldman, P. S., and Nauta, W. J. H. 1976. Autoradiographic demonstration of a projection for prefrontal association cortex to the superior colliculus in the rhesus monkey. Brain Res. 116:145–149.PubMedCrossRefGoogle Scholar
  19. Gordon, B. 1973. Receptive fields in deep layers of cat superior colliculus. J. Neurophysiol. 36:157–178.PubMedGoogle Scholar
  20. Harting, J. K., and Noback, C. R. 1971. Subcortical projections from the visual cortex in the tree shrew (Tupaia glis).Brain Res. 25:21–33.PubMedCrossRefGoogle Scholar
  21. Harting, J. K., Hall, W. C., and Diamond, I. T. 1972. Evolution of the pulvinar. Brain Behau. Evol. 6:424–452.CrossRefGoogle Scholar
  22. Harting, J. K., Hall, W. C., Diamond, I. T., and Martin, G. F. 1973. Anterograde degeneration study of the superior colliculus in Tupaia glis: Evidence for a subdivision between superficial and deep layers. J. Comp. Neurol. 148:361–386.PubMedCrossRefGoogle Scholar
  23. Hendrickson, A., Wilson, M. E., and Toyne, M. J. 1970. The distribution of optic nerve fibers in Macaca mulatta.Brain Res. 23:425–427.PubMedCrossRefGoogle Scholar
  24. Hubel, D. H., LeVay, S., and Wiesel, T. N. 1975. Mode of termination of retinotectal fibers in macaque monkey: An autoradiographic study. Brain Res. 96:25–40.PubMedCrossRefGoogle Scholar
  25. Huber, G. C., and Crosby, E. C. 1933. A phylogenetic consideration of the optic tectum. Proc. Nat. Acad. Sci. U.S.A. 19(1):15–22.CrossRefGoogle Scholar
  26. Huber, G. C., and Crosby, E. C. 1943. A comparison of the mammalian and reptilian tecta. J. Comp. Neurol. 78:133–168.CrossRefGoogle Scholar
  27. Humphrey, N. K. 1968. Responses to visual stimuli of units in the superior colliculus of rats and monkeys. Exp. Neurol. 20:312–340.PubMedCrossRefGoogle Scholar
  28. Kaas, J. H., Harting, J. K., and Guillery, R. W. 1974. Representation of complete retina in the contralateral superior colliculus of some mammals. Brain Res. 65:343–346.PubMedCrossRefGoogle Scholar
  29. Kadoya, S., Massopust, L. C., Jr., and Wolin, L. R. 1971a. Striate cortex-superior colliculus projections in squirrel monkey. Exp. Neurol. 32:98–110.PubMedCrossRefGoogle Scholar
  30. Kadoya, S., Wolin, L. R., and Massopust, L. C. Jr., 1971b. Photically evoked unit activity in the tectum opticum of the squirrel monkey. J. Comp. Neurol. 142:495–508.PubMedCrossRefGoogle Scholar
  31. Kadoya, S., Wolin, L. R., Massopust, L. C. Jr., 1971c. Collicular unit responses to monochromatic stimulation in squirrel monkey. Brain Res. 32:251–254.PubMedCrossRefGoogle Scholar
  32. Keating, E. G. 1974. Impaired orientation after primate tectal lesions. Brain Res. 67:538–541.CrossRefGoogle Scholar
  33. Kiinzle, H., Akert, K., and Wurtz, R. H. 1976. Projection of area 8 (frontal eye field) to superior colliculus in the monkey. An autoradiographic study. Brain Res. 117:487–492.CrossRefGoogle Scholar
  34. Kuypers, H. G. J. M., and Lawrence, D. G. 1967. Cortical projections to the red nucleus and the brain stem in the rhesus monkey. Brain Res. 4:151–188.PubMedCrossRefGoogle Scholar
  35. Laemle, K. L. 1968. Retinal projections of Tupaia glis.Brain Behau. Euol. 1:473–499.CrossRefGoogle Scholar
  36. Lane, R. H., Allman, J. M., and Kaas, J. H. 1971. Representation of the visual field in the superior colliculus of the grey squirrel (Sciurus carolinensis) and the tree shrew (Tupaia glis).Brain Res. 26:277–292.PubMedGoogle Scholar
  37. Lane, R. H., Allman, J. M., Kaas, J. H., and Miegin, F. M. 1973. The visuo-topic organization of the superior colliculus of the owl monkey (Aotus trwirgatus) and the bush baby (Galago senegalensis).Brain Res. 60:335–349.PubMedCrossRefGoogle Scholar
  38. Lund, R. D. 1969. Synaptic patterns of the superficial layers of the superior colliculus of the rat. J. Comp. Neurol. 135:179–208.PubMedCrossRefGoogle Scholar
  39. Lund, R. D. 1970. Structural organization of the superior colliculus and dorsal lateral geniculate body of the rat. J. Physiol. Soc. Jap. 32:555–556.PubMedGoogle Scholar
  40. Lund, R. D. 1972. Synaptic patterns in the superficial layers of the superior colliculus of the monkey, Macaca mulatta.Exp. Brain Res. 75:194–211.Google Scholar
  41. Lund, R. D., and Lund, J. S. 1971a. Synaptic adjustment after deafferentation of the superior colliculus of the rat. Science 171:804–807.PubMedCrossRefGoogle Scholar
  42. Lund, R. D., and Lund, J. S. 1971b. Modifications of synaptic patterns in the superior colliculus of the rat during development and following deafferentation. Vision Res. 3:281–298.PubMedCrossRefGoogle Scholar
  43. Lynch, J. C., Yin, T. C. T., Talbot, W. H., and Mountcastle, V. B. 1975. A cortical source of command signals for visually evoked saccadic movements of the eyes in the monkey. Soc. Neurosci. 1:59 (Abstract).Google Scholar
  44. Mathers, L. H. 1971. Tectal projection to the posterior thalamus of the squirrel monkey. Brain Res. 35:295–298.PubMedCrossRefGoogle Scholar
  45. Mehler, W. R. 1969. Some neurological species differences—a posteriori.Ann. N.Y. Acad. Sci. 167:424–468.CrossRefGoogle Scholar
  46. Mehler, W. R., Feferman, M. E., and Nauta, W. J. H. 1960. Ascending axon degeneration following anterolateral cordotomy. An experimental study in the monkey. Brain 83:718–750.PubMedCrossRefGoogle Scholar
  47. Mohler, C. W., and Wurtz, R. H. 1975. A new view of visual-oculomotor integration in monkey superior colliculus. Soc. Neurosci. 1:231. (Abstract).Google Scholar
  48. Moore, R. Y., and Goldberg, J. M. 1966. Projections of the inferior colliculus in the monkey. Exp. Neurol. 14:429–438.PubMedCrossRefGoogle Scholar
  49. Myers, R. E. 1963. Projections of superior colliculus in monkey. Anat. Rec. 145:264.Google Scholar
  50. Oh, S.-Y. 1973. Zur Cytoarchitektonik der Colliculi superiores des Mittelhirns bei Cer-copitheciden. Z. Mikrosk. Anat. Forsch. 87:410–422.PubMedGoogle Scholar
  51. Olszewski, J., and Baxter, D. 1954. Cytoarchitecture of the Human Brain Stem. J. B. Lippincott, Philadelphia. 199 pp.Google Scholar
  52. Pasik, P., and Pasik, T. 1964. Oculomotor functions in monkeys with lesions of the cerebrum and the superior colliculi. In M. B. Bender (ed.). The Oculomotor System. Harper and Row, New York. Pp. 40–80.Google Scholar
  53. Pasik, T., Pasik, P., and Bender, M. B. 1966. The superior colliculus and eye movements. Arch. Neurol. (Chicago) 15:420–436.CrossRefGoogle Scholar
  54. Peele, T. L. 1942. Cytoarchitecture of individual parietal areas in the monkey (Macaca mulatto) and the distribution of efferent fibers. J. Comp. Neurol. 77:693–737.CrossRefGoogle Scholar
  55. Pierson, R. J., and Carpenter, M. B. 1974. Anatomical analysis of pupillary reflex pathways in the rhesus monkey. J. Comp. Neurol. 158:121–144.PubMedCrossRefGoogle Scholar
  56. Ramóny Cajal, S. 1955. Histologie du système nerveux de l’homme et des vertébrés. Vol. II. Consejo Superior de Investigaciones Cientifícas. Instituto Ramón y Cajal. Madrid. Pp. 174–195.Google Scholar
  57. Robinson, D. A. 1972. Eye movements evoked by collicular stimulation in the adult monkey. Vision Res. 72:1795–1808.CrossRefGoogle Scholar
  58. Scheibel, M. E., Davies, T. L., and Scheibel, A. B. 1973. Maturation of reticular dendrites: Loss of spines and development of bundles. Exp. Neurol. 35:301–310.CrossRefGoogle Scholar
  59. Schiller, P. H. 1972. The role of the monkey superior colliculus in eye movement and vision. Invest. Ophthalmol. 11:451–460.PubMedGoogle Scholar
  60. Schiller, P. H., and Koerner, F. 1971. Discharge characteristics of single units in superior colliculus of the alert rhesus monkey. J. Neurophysiol. 35:920–936.Google Scholar
  61. Schiller, P. H., and Malpeli, J. G. 1977. Properties and tectal projections of monkey retinal ganglion cells. J. Neurophysiol. 40:428–445.PubMedGoogle Scholar
  62. Schiller, P. H., and Stryker, M. 1972. Single-unit recording and stimulation in superior colliculus of the alert rhesus monkey. J. Neurophysiol. 35:915–924.PubMedGoogle Scholar
  63. Schiller, P. H., Stryker, M., Cynader, M., and Berman, N. 1974. Response characteristics of single cells in the monkey superior colliculus following ablation or cooling of visual cortex. J. Neurophysiol. 37:181–194.PubMedGoogle Scholar
  64. Schroeder, D. M., and Jane, J. A. 1971. Projections of dorsal column nuclei and spinal cord to brain stem and thalamus in the tree shrew, Tupaia glis.J. Comp. Neurol. 142:309–350.PubMedCrossRefGoogle Scholar
  65. Spatz, W. B., Tigges, J., and Tigges, M. 1970. Subcortical projections, cortical associations, and some intrinsic interlaminar connections of the striate cortex in the squirrel monkey (Saimiri).J. Comp. Neurol. 140:155–174.PubMedCrossRefGoogle Scholar
  66. Sprague, J. M. 1975. Mammalian tectum: Intrinsic organization, afferent inputs and integrative mechanisms. In Sensorimotor Function of the Midbrain Tectum. Neurosci. Res. Programs Bull. 13(2):204–213.Google Scholar
  67. Sprague, J. M., Berlucchi, G., and Rizzolatti, G. 1973. The role of the superior colliculus and pretectum in vision and visually guided behavior. In R. Jung (ed.). Handbook of Sensory Physiology, B, Vol. VII/3. Springer, New York. Pp.27–101.Google Scholar
  68. Sterling, P. 1971. Receptive fields and synaptic organization of the superficial gray layer of the cat superior colliculus. Vision Res. Suppl. 3:309–328.CrossRefGoogle Scholar
  69. Tigges, J., and O’steen, K. W. 1974. Termination of retinofugal fibers in squirrel monkey: A re-investigation using autoradiographic methods. Brain Res. 79:489–495.PubMedCrossRefGoogle Scholar
  70. Tigges, J., and Tigges, M. 1969. The accessory optic system and other fibers of the squirrel monkey. Folia Primatol. 10:245–262.PubMedCrossRefGoogle Scholar
  71. Tigges, J., Tigges, M., and Kalaha, C. S. 1973. Efferent connections of area 17 in Galago. Amer. J. Phys. Anthropol. 38:393–398.CrossRefGoogle Scholar
  72. Tigges, M., and Tigges, J. 1970. The retinofugal fibers and their terminal nuclei in Galago crassicaudatus (Primates). J. Comp. Neurol. 138:87–102.PubMedCrossRefGoogle Scholar
  73. Tigges, M, Tigges, J., Luttrel, G. L., and Frazier, C. M. 1973. Ultrastructural changes in the superficial layers of the superior colliculus in Galago crassicaudatus (Primates) after eye enucleation. Z. Zellforsch. Mikrosk. Anat. 140:291–307.PubMedCrossRefGoogle Scholar
  74. Tigges, V. J. 1966. Ein experimenteller Beitrag zum subkortikalen optischen System von Tupaia glis.Folia Primatol. 4:103–123.PubMedCrossRefGoogle Scholar
  75. Trevarthen, C. 1970. Experimental evidence for a brainstem contribution to visual perception in man. Brain Behav. Evol. 3:338–352.PubMedCrossRefGoogle Scholar
  76. Trevarthen, C., and Sperry, R. W. 1973. Perceptual unity of the ambient visual field in human commissurotomy patients. Brain 96:547–570.PubMedCrossRefGoogle Scholar
  77. Whitlock, D. G., and Nauta, W. J. H. 1956. Subcortical projections from the temporal neocortex in Macaca mulatta.J. Comp. Neurol. 106:183–212.PubMedCrossRefGoogle Scholar
  78. Williams, R. L., and Warwick, R. 1975. Functional Neuroanatomy of Man. W. B. Saunders, Philadelphia.Google Scholar
  79. Wilson, M. E., and Toyne, M. J. 1970. Retino-tectal and cortico-tectal projections in Macaca mulatta.Brain Res. 24:395–406.PubMedCrossRefGoogle Scholar
  80. Wurtz, R. H., and Goldberg, M. E. 1972a. Activity of superior colliculus in behaving monkey. III. Cells discharging before eye movements. J. Neurophysiol. 35:575–586.PubMedGoogle Scholar
  81. Wurtz, R. H., and Goldberg, M. E. 1972b. Activity of superior colliculus in behaving monkey. IV. Effects of lesions on eye movements. J. Neurophysiol. 35:587–596.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Roberta Pierson Pentney
    • 1
  • John R. Cotter
    • 1
  1. 1.Department of Anatomical SciencesState University of New YorkBuffaloUSA

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