Practical Dietary Research Design and Applications for Southwestern American Indians

  • Margaret E. Hendrikx


Some of the practical problems in planning human research studies on effects of fiber feeding are the selection of type and amount of fiber, dietary calculation of the fiber and nutrients, patient acceptance, study duration, and differences in populations. In both planning and evaluation of research, there are difficulties in interpretation of the literature because of differences in terminology and analytic technique.


Bile Acid Bile Salt Chenodeoxycholic Acid Cholesterol Gallstone Biliary Cholesterol 
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  1. 1.
    Adler, R. D., Bennion, L. J., Duane, W. C. and Grundy, S. M., 1975, Effects of low-dose chenodeoxycholic acid feeding on biliary lipid metabolism, Gastroenterology, 68: 326.Google Scholar
  2. 2.
    Altman, P. L., Dittmer, D. S., 1968, Metabolism, Fed. Am. Soc. Exptl. Biol., Besthesda, Md., p. 515.Google Scholar
  3. 3.
    Bell, G. D., 1974, The present position concerning gallstones dissolution, Gut., 15: 913.CrossRefGoogle Scholar
  4. 4.
    Crampton, E. W. and Maynard, L. A., 1938, The relation of cellulose and lignin content to the nutritive value of animal feeds, J. Nutr., 15: 383.Google Scholar
  5. 5.
    Crane, Milton, G., Harris, J. J., Herber, R., Shankel, S. and Specht, N., 1969, Excessive fluid retention related to cellulose ingestion: studies on two patients, Metabolism, 18: 945.Google Scholar
  6. 6.
    Crowther, J. S., Drasar, B. S., Goddard, P., Hill, M. J. and Johnson, K., 1973, The effect of a chemically defined diet on faecal flora and faecal steroid concentration, Gut., 14: 790.CrossRefGoogle Scholar
  7. 7.
    Cummings, J. H., 1973, Progress report on dietary fiber, Gut., 14: 69.CrossRefGoogle Scholar
  8. 8.
    Danzinger, R. G., Hofmann, A. F., Schoenfield, L. J., and Thistle, J. L., 1972, Dissolution of cholesterol gallstones by chenodeoxycholic acid, N. Eng. J. Med., 286: 1.CrossRefGoogle Scholar
  9. 9.
    Davidson, S.,and Passmore, R., Human Nutrition and Dietetics 4th edition ( Philadelphia: Lea and Febiger, 1973 ).Google Scholar
  10. 10.
    Eastwood, M. A., and Girwood, R. H., 1964, The meaning of high- and low-residue diets, Gastroenterology, 47: 649.Google Scholar
  11. 11.
    Eastwood, M. A., and Girwood, R. H., 1968, Lignin: a bile-salt sequestering agent, Lancet, 2: 1170.CrossRefGoogle Scholar
  12. 12.
    Eastwood, M. A., and Hamilton, D., 1973, Studies on the absorption of bile salts to nonabsorbed components of the diet, Biochimica et Biophysica Acta, 152: 165.Google Scholar
  13. 13.
    Falaiye, J. M., 1974, Bile salt patterns in Nigerians on a high-fibre diet, Lancet, 1: 1002.CrossRefGoogle Scholar
  14. 14.
    Goodhart, R. S., and Shils, M. D., Modern Nutrition in Health and Disease, 5th edition, ( Philadelphia: Lea and Febiger, 1973 ) p 102.Google Scholar
  15. 15.
    Grundy, S. M., Metzger, A. L., and Adler, R. D., 1972, Mechanisms of lithogenic bile formation in American Indian women with and without cholesterol gallstones, J. of Clin. Invest., 15: 3026.CrossRefGoogle Scholar
  16. 16.
    Guthrie, H. A., Introductory Nutrition (St. Louis: C. V. Mosby, 1971 ) p. 25.Google Scholar
  17. 17.
    Heaton, K. W., 1973, Food fibre as an obstacle to energy intake, Lancet, 2: 1418.CrossRefGoogle Scholar
  18. 18.
    Heaton, K. W., and Pomare, E. W., 1974, Effect of bran on blood lipids and calcium, Lancet, 1: 49.CrossRefGoogle Scholar
  19. 19.
    Heaton, K. W., and Pomare, E. W., 1975, Bran and blood lipids, Lancet, 5: 800.Google Scholar
  20. 20.
    James, W. P. T., and Cummings, J. H., 1974, Dietary fibre and energy regulation, Lancet, 1: 61.CrossRefGoogle Scholar
  21. 21.
    Jeffrys, D. B., 1974, The effect of dietary fibre on the response to orally administered glucose, Proc. of the Nutr. Soc., 33: 11A.Google Scholar
  22. 22.
    Kritchevsky, D., 1974, Isocaloric, isogravic diets in rats, III, Nutr. Rep. Int., 9: 301.Google Scholar
  23. 23.
    Kritchevsky, D., and Story, J. A., 1974, Binding of bile salts in vitro by nonnutritive fiber, J. Nutr., 104: 458.Google Scholar
  24. 24.
    Leung, W. W., Butrum, R. R., and Chang, F. H., 1972, Food composition table for use in East Asia, Pub. No. 73, (NIH), P. 9, DHEW.Google Scholar
  25. 25.
    Medical World News, Roughage in the diet, September 6, 1974, 35.Google Scholar
  26. 26.
    Pomare, E. W., and Heaton, K. W., 1973, Alteration of bile salt metabolism by dietary fibre (bran), Brit. Med. J., 4: 262.CrossRefGoogle Scholar
  27. 27.
    Reilly, R., and Kirsner, J. B., 1975, Fiber deficiency and colonic disorders, Am. J. Clin. Nutr., 28: 293.Google Scholar
  28. 28.
    Robertson, J. B., 1975, Personal communication.Google Scholar
  29. 29.
    Saunders, R. M. and Walker, H. G., 1969, The sugars of wheat bran, Cereal Chemistry, 46: 85.Google Scholar
  30. 30.
    Sievers, M. L., 1966, Disease patterns among southwestern Indians, P. H. Reports, 81: 1075.Google Scholar
  31. 31.
    Sievers, M. L., and Hendrikx, M. E., 1972, Two weight-reduction programs among southwestern Indians, Health Services Reports, 87: 530.CrossRefGoogle Scholar
  32. 32.
    Spiller, G. A., and Amen, R. J., 1974, Research on dietary fibre, Lancet, 2: 1259.CrossRefGoogle Scholar
  33. 33.
    Trowell, H., 1974, Diabetes mellitus death rates in England and Wales, 1920–1970, and food supplies, Lancet, 2: 998.CrossRefGoogle Scholar
  34. 34.
    Trowell, H., 1975, Bran and blood lipids, Lancet, 2: 801.Google Scholar
  35. 35.
    Van Soest, P. J., and McQueen, R. W., 1973, Symposium on fibre in human nutrition, Proceedings of the Nutrition Society, 32: 123.CrossRefGoogle Scholar
  36. 36.
    Visek, W. J., and Robertson, J. B., 1973, Cornell Nutrition Conference, p. 18.Google Scholar
  37. 37.
    Watt, B. K., and Merrill, A. L., 1963, Composition of foods, raw, processed and prepared, Ag. Handbook No. 8, p. 66.Google Scholar
  38. 38.
    Whyte, H. M., Nestel, P. J., and Pryke, E. S., 1973, Bile acid and cholesterol excretion with carbohydrate-rich diets, J. Lab. Clin. Med., 81: 818.Google Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Margaret E. Hendrikx
    • 1
  1. 1.Metabolism, and Digestive DiseasesNational Institute of ArthritisPhoenixUSA

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