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Coupling between the Charge-Separating Devices of the Mitochondrion: Intra- or Extramembrane?

  • Harold Baum

Abstract

This past year has seen such a plethora of reviews and “mini-reviews” on the mechanism of oxidative phosphorylation (e.g., refs. 1–3) that it would be both tedious and arrogant of me to add to their number. Instead, I propose to offer some personal thoughts on the subject, illustrated by reference to some of our own work, past and present. This selection is not intended to claim any particular priorities; indeed, in some cases the examples are more of pitfalls than of positive contributions. The common thread is that when the contributions have proved to be useful they have been based on the solid conceptual framework of the organization of the inner mitochondrial membrane in general and of the respiratory chain in particular, which is one of the great contributions that David Green has made to science.

Keywords

Oxidative Phosphorylation Respiratory Chain Charge Separation Conformational Energy Osmotic Gradient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Harold Baum
    • 1
  1. 1.Department of Biochemistry, Chelsea CollegeUniversity of LondonLondonUK

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