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Microsomal Oxidases

  • Daniel M. Ziegler

Abstract

Most eukaryotic cells contain a membranous network—the endoplasmic reticulum—that forms vesicular fragments when the cells are homogenized. These vesicles, separated from homogenates by differential centrifugation, make up the major membrane components(1) in the fraction usually referred to as “microsomes.” Microsomal fractions derived from mammalian tissues contain oxidoreductases that vary in concentration and specificity not only in different tissues but also in the same tissue of a single species as a function of development, sex, or exposure to different environmental conditions. Changes in the concentration of specific enzymes can be especially marked in liver microsomes since the endoplasmic reticulum of hepatocytes apparently readily adapts to meet changing physiological or environmental conditions.

Keywords

Liver Microsome Tertiary Amine Amine Oxidase Microsomal Protein Terminal Oxidase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Daniel M. Ziegler
    • 1
  1. 1.Clayton Foundation Biochemical Institute and Department of ChemistryUniversity of Texas at AustinAustinUSA

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